Amyotrophic Lateral Sclerosis is a rare, progressive neurodegenerative disease that primarily affects motor neurons in the body, which are responsible for controlling muscle activity.
As these neurons gradually die or lose function, the brain and spinal cord can't send the necessary signals to muscles, leading to the muscles getting weaker and atrophying. Simply put, it's a gradual muscle wasting disease, which is what Stephen Hawking had.
Although this era is rapidly developing, there still hasn't been a breakthrough in medical technology for ALS. Fortunately, Xia Anyang's substantial wealth can support his mother-in-law, but she has to be in Mei City for convalescence, confined to the hospital to slow the progression of the disease.
No matter how busy they are, every week Xia Nuo and her parents make time to accompany Grandma for walks and chats, sharing recent amusing events, and Fang You occasionally joins them to visit Xia Nuo's grandmother.