The number of Deadpool comic series is difficult to pin down precisely. However, if you consider all the various runs and special editions, it's likely well over 20.
Deadpool is the central character, no doubt. But in the first series, there are others. Besides Cable and Weasel, there are villains like Ajax. Ajax has a history with Deadpool and is part of what drives some of the early storylines. There are also some minor characters like Blind Al, who is Deadpool's roommate in a way. She adds an interesting dynamic to Deadpool's living situation and his overall story.
The main features often include Deadpool's unique sense of humor. His fourth - wall - breaking antics are quite prominent. Also, the action - packed and often over - the - top fight scenes are a big part of it. The graphic novels usually have a distinct art style that helps bring Deadpool's crazy world to life.
Deadpool became Deadpool through a series of complex and sometimes convoluted events in the comics. He was originally a mercenary named Wade Wilson, who underwent experimental treatments that gave him his unique powers and personality.
There is a loose link. The version of Deadpool in Wolverine Origins provided a starting point, but the standalone Deadpool movies developed his character and story in a more distinct and expanded way, deviating from the initial portrayal to create a more focused and engaging narrative.
It's a bit of a mixed bag. While there's a link, the portrayal of Deadpool in Wolverine Origins doesn't fully align with his later, more developed storyline. Some elements were changed or not fully explored.