In my opinion, it's highly unlikely. Goku has mastered multiple forms and techniques that give him a wide range of powers. Saitama's one-punch style might not be effective against Goku's diverse skills and battle experience.
I don't think there's a clear winner. Both Manga Goku and Manga Saitama have unique and powerful abilities. It could come down to strategy, luck, or even the author's imagination!
I think Saitama is stronger. His power is seemingly limitless and he has never struggled in a fight. Goku, although powerful, has had many intense battles where he was pushed to his limits.
In my opinion, Saitama doesn't have a chance against Goku. Goku has mastered multiple forms of Super Saiyan and has fought incredibly powerful foes across multiple universes. Saitama's strength is impressive, but it's not on the same level as Goku's.
It's really hard to say. Goku has the ability to keep getting stronger through intense battles and transformations. However, Saitama has the power to defeat any opponent with just one punch. If we consider Goku's Super Saiyan Blue form, he has an incredibly high power level. But Saitama's strength has no known limits yet. It could go either way depending on the circumstances of the fight, like if Goku has time to power up or if Saitama can land his punch first.
I really don't know anything about the 'vd tyagi' real story as the name doesn't ring a bell. There are so many people in the world, and without further context, it's impossible to know their story.
Obviously, Elena should be the main character. She could be joined by her friends from the original 'vd' story. For example, Stefan and Damon who could either help or hinder her in her journey of 'becoming'.
One idea could be Elena discovers a hidden power within herself that she has to learn to control. It could lead to her having to face new enemies or challenges in the 'vd' world.