In the manga, Gohan never managed to defeat Goku. Their battles often ended with Goku coming out on top or the fight being interrupted for some reason.
In my opinion, it's highly unlikely. Goku has mastered multiple forms and techniques that give him a wide range of powers. Saitama's one-punch style might not be effective against Goku's diverse skills and battle experience.
I don't think there's a clear winner. Both Manga Goku and Manga Saitama have unique and powerful abilities. It could come down to strategy, luck, or even the author's imagination!
Goku's victory over Hit in the manga was the result of his perseverance and the ability to surprise Hit with unexpected moves. Also, his experience in battles played a significant role.
Goku would probably be very friendly with Luffy. They both love to fight strong opponents and have a sense of adventure. Goku might be a bit confused by some of the wacky things in the One Piece world like the Devil Fruits at first, but he'd quickly adapt. He'd also likely be impressed by the determination of the other characters like Zoro and Sanji.