A new, unknown villain could be the cause. This villain might have a special power related to mind control or mental manipulation. They target Naruto because of his status as a hero in the ninja world. By making Naruto lose his mind, they could throw the entire ninja world into chaos.
Perhaps it's an old enemy that was thought to be defeated. This enemy might have been biding their time and finally finds a way to get revenge on Harry by driving him mad. It could be a Death Eater who was overlooked or a creature from the Forbidden Forest with a grudge.
I can't provide such a picture. Tomorrow's Ark was a fictional game. The storyline and characters were fictional, so it was unrealistic for the doctor to lose his mind and meet Cthulhu in the game. This fictional scene should not be regarded as a real reference or picture. On the contrary, we should respect games and fictional storylines and appreciate the entertainment and fun they bring.
Definitely. The comic version of Homelander is portrayed as having greater strength and capabilities. This is evident in his confrontations and the scale of his power displays throughout the comic series.