At the moment, there's no clear indication that Ultimate Spider-Man comic is coming back. Maybe we'll hear something in the future, but right now, it's a mystery.
The main villain in Iron Man 2 is Ivan Vanko. His father worked with Howard Stark on the arc reactor technology. But his father was deported and died in poverty. Ivan blames the Stark family for this. So he uses his own engineering genius to create his own arc reactor - like weaponry, specifically the whips, and sets out to take revenge on Tony Stark.
In some comic arcs, Iron Man does return. It often depends on the creative direction and plot developments. Sometimes, his return is part of a larger narrative to restore balance or address a new threat.
Sure. Tony Stark, who is Iron Man, was a billionaire, playboy, and genius inventor. He was captured by terrorists and forced to build a weapon. Instead, he created a powered suit of armor to escape. This was the origin of his Iron Man suits. Later, he refined the suit and used it to fight against evil, protect the world, and became one of the founding members of the Avengers.