The main differences between the giantess gts anime and manga lie in their presentation. The anime could have better sound and animation to bring the scenes to life, but the manga might offer a more immersive reading experience with its unique panel layout and storytelling techniques.
It could be Meg. Since she's often the outcast in the show, turning her into a giantess could be an interesting twist. It would give her a new - and very literal - form of power and attention that she doesn't usually get in the show.
A 'giantess cuckold story' typically involves a fictional scenario where there is a giantess character in a relationship dynamic that may involve elements similar to the concept of cuckoldry in some way. However, it's often a very niche and specific type of fictional or fantastical narrative.
No. Popular stories usually have themes that are more widely understood and appealing. 'Giantess cuckold stories' are extremely niche. They involve rather complex and not - so - common relationship dynamics along with the very specific idea of a giantess. Most people are not drawn to such stories as they are far from the typical story elements that are popular in mainstream literature, movies or other forms of media.
Giantess girl comics are known for their imaginative scenarios. They might feature giantesses interacting with normal-sized people in unexpected ways. The themes can range from adventure to romance, depending on the creator's vision.
One story could be about a tiny world where giantess girls' feet are like mountains. The little people in this world have to be careful not to get stepped on by these huge feet. They might build their villages far away from the areas where the giantess girls walk.