It can start with mutual distrust. Doomguy is used to killing demons, and the female demon is afraid of him. But when they are forced into a situation where they have to rely on each other to survive, like being trapped in a small area surrounded by more powerful demons, they start to see each other in a new light. They begin to communicate, first out of necessity, and then gradually become more open with each other.
The Doomguy was once a marine. He was sent to Mars to investigate some strange happenings on a Union Aerospace Corporation (UAC) facility. The UAC had been messing around with teleportation technology and had accidentally opened portals to Hell. Doomguy found himself in the middle of a demonic invasion. His initial experiences on Mars were filled with fighting off hordes of demons, and this was just the start of his journey to become the ultimate demon - slayer.
There's a fanfic called 'Doomguy in the Hidden Leaf'. In this one, Doomguy gets transported to the Naruto universe. It's interesting to see how he interacts with the different ninja clans, especially when his no - nonsense attitude clashes with the more traditional ways of the Leaf Village. It's a short but engaging read.
The key elements include the Union Aerospace Corporation (UAC). Their unethical and dangerous experiments with teleportation on Mars were crucial. Doomguy being a marine is also important as it provided him with the discipline and some level of combat ability. The sudden demonic invasion that he had to face on Mars was the turning point. It forced him to adapt and start his journey as the Doomguy. Without these elements, his origin story would be completely different.
Well, in a 'naruto is doomguy' fanfiction, Naruto would find himself in a completely different and much darker world than his own. He'd have to quickly learn how to handle Doomguy's arsenal of weapons. His natural athleticism and combat skills as a ninja would be put to the test in a new way against the demonic hordes. The story could also involve Naruto trying to find a way back to his own world while dealing with the constant threat of the demons. It could be a story of adaptation, survival, and heroism as Naruto tries to use his unique skills to fight in a world that's not his own.
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I recommend 'The Myths Will Come True in the Magic World' to you. The main character was a modern person who regarded Chinese as the language of the gods and had accidentally transmigrated to another world. In this world, the language had become a mysterious language similar to Latino, and only the protagonist could understand Mandarin. In order to return to his own world, the protagonist began his own adventure.
Well, it could be about them teaming up to fight some sort of super - evil that combines the threats from both their worlds. Maybe some demons are using goblins as minions and they have to work together to stop this chaos.
Dante from Devil May Cry would be an excellent character to pair with Doomguy. Dante is a stylish demon hunter, and when combined with Doomguy's brute force approach, it would create some really cool action scenes. Also, Samus Aran from Metroid could be a good match. Samus' exploration skills and Doomguy's combat abilities could lead to an interesting story, especially if they are in a shared alien - infested environment.