In Pacific Rim 2, the story continues after the first movie. New Jaegers are built. There are new threats emerging from the Kaiju. The main characters face a lot of challenges in trying to protect the world. They have to deal with new types of Kaiju and also some internal conflicts within their own organization.
The key points in the Pacific Rim 2 full story include the continued threat of the Kaiju. The development of new technology for the Jaegers is significant. It's also about the characters growing and learning to face the challenges. There are power struggles within the organization that deals with the Kaiju defense. And the battles between the Jaegers and the Kaiju are always a major part of the story.
Definitely not. Pacific Rim has no connection to manga. It was conceived and brought to life specifically as a cinematic production with its own distinct storyline and universe.
It's a story of humans fighting against giant monsters from another dimension using huge robots. The robots are piloted by pairs of humans who need to have a mental connection to operate them effectively.