The Naruto manga itself doesn't have fillers. Fillers are a common thing in anime to extend the runtime or bridge gaps in the manga's story. But the manga sticks strictly to the main plot.
Eventually, Naruto could grow resentful. If the ignoring persists for a long time, he might start to think that Kakashi doesn't care about him at all. This could change Naruto's attitude towards Kakashi and might even make him more rebellious in his training or actions. However, deep down, he still probably hopes for Kakashi's recognition and approval.
Naruto would probably be extremely hurt. He has always considered Hinata a friend and perhaps more. Betrayal from her would be a huge blow to his trusting nature. He might initially be in denial, not wanting to believe that Hinata could do such a thing.
At first, Naruto would be completely shocked. He has always seen Hinata as a loyal friend and someone who has deep feelings for him. So the idea of her betrayal would be hard to fathom. He might try to deny it at first.
He would probably be very angry. Naruto has always been a free - spirited person, and being experimented on against his will would be a huge violation of his rights. He might initially try to resist physically, but as the situation gets more complex, he could start to plot his escape and revenge.