I think young Sasuke would have a very intense reaction. He was so consumed by his hatred for Itachi at that young age. A Sasuke vs Itachi fanfiction would be like a trigger for him. He would be eager to see how the fictional fight is portrayed. If Sasuke in the fanfiction is shown as strong, it might fuel his own ego and make him strive even harder to become powerful. However, if the fanfiction shows Itachi as superior, it could enrage him. He might feel that it undermines his own goal of defeating Itachi and he might even want to find the writer to correct their 'wrong' view.
He might feel anger. Since he was so set on revenge against Itachi, any portrayal that didn't match his view of himself as the victor could make him angry.
Wonder Woman is another character that might be paired with Itachi. Her Amazonian warrior heritage and Itachi's shinobi skills can be compared and contrasted. Their different views on justice, with Wonder Woman coming from a more idealistic place and Itachi having a more pragmatic approach, can lead to some great character - driven storylines in fanfiction.
Naruto would adapt to Itachi's life in several ways. Socially, he'd have to get used to Itachi's connections and rivalries. For instance, his relationship with Kisame would be different as Naruto. He might try to influence Kisame in a more positive way. Emotionally, he'd have to deal with Itachi's internal struggles. Itachi had a lot of guilt and secrets, and Naruto would have to either come to terms with them or find a way to resolve them. And in terms of combat, he'd practice Itachi's signature moves over and over to make sure he could use them effectively in battle.
They could develop a mentor - mentee relationship. Itachi uses his knowledge of the Sharingan to teach Naruto new combat techniques. As they train together, they bond over their shared experiences of loss and their desire to protect the people they care about. Naruto might also help Itachi come to terms with his past actions and find some peace within himself.
Itachi's personality could become more outwardly friendly. In the ninja world, he had to keep many secrets and be aloof. But in the wizarding world as Harry Potter, he might find it easier to let people in. He may also be more assertive in a different way. Instead of silently following orders like in his past life, he could take the lead in situations, using his own judgment based on his past experiences and newfound magical knowledge.
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While waiting for the TV series, he could also click on the link below to read the classic original work of " The Legend of Mortal Cultivation "!