I think young Sasuke would have a very intense reaction. He was so consumed by his hatred for Itachi at that young age. A Sasuke vs Itachi fanfiction would be like a trigger for him. He would be eager to see how the fictional fight is portrayed. If Sasuke in the fanfiction is shown as strong, it might fuel his own ego and make him strive even harder to become powerful. However, if the fanfiction shows Itachi as superior, it could enrage him. He might feel that it undermines his own goal of defeating Itachi and he might even want to find the writer to correct their 'wrong' view.
In many fanfictions, the scenario of Naruto and Itachi killing the Uchiha clan is a very interesting but also controversial topic. One aspect could be the change in Naruto's character. Usually, Naruto stands for justice and protecting others. If he were involved in such a massacre, it would be a huge deviation from his original character. Maybe in the fanfiction, there could be some extreme situations that force him to do so, like being mind - controlled or having some false information.
In some fanfictions, a possible motivation for Naruto could be to prevent a greater evil. Maybe he was tricked into believing that the Uchiha clan was about to start a war that would destroy the entire ninja world. So, he thought that by taking part in killing the clan, he could save more lives in the long run.
Sasuke could also be confused. He has always had a mix of emotions towards Itachi, including love, hate, and envy. Being kidnapped by him would add another layer of confusion. He might wonder if Itachi has some new plan or if he's finally going to reveal some long - hidden truth. So, he might hold back on his full - fledged resistance and wait to see what Itachi has to say.
Sasuke would likely be enraged. Naruto is his rival and also, in a way, his friend. He would immediately set out to find Naruto and confront Itachi. Sasuke has a strong sense of pride and would not let his brother get away with this.
Sasuke would probably be very confused at first. He has spent so much time hating Itachi for what he did to the Uchiha clan. Seeing Naruto befriend Itachi would make him question his own long - held beliefs. He might initially be angry with Naruto for seemingly siding with his enemy.
He might feel anger. Since he was so set on revenge against Itachi, any portrayal that didn't match his view of himself as the victor could make him angry.
There would be other fans who might be intrigued. They like to explore different 'what - if' scenarios in fanfiction. They would see it as a creative way to explore the characters in a new light, even if it goes against the canon. However, they would also be aware that it's just a fictional alternative and not the real Naruto story.
I recommend the two novels,"The Daily Life of Uchiha Nano" and "Revenge against Uchiha Weasel from the Night of the Extermination." "Uchiha Nano's Daily Life" was a Naruto manga. There was no female protagonist in it, and it was mainly about the plot and humor. "Revenge against Uchiha Weasel from the Night of Family Extermination" was a derivative doujinshi novel. The male protagonist was Uchiha Weasel, and the plot was more complicated. I hope you like this fairy's recommendation. Muah ~😗
Sakura might be heartbroken at first. She has always been in love with Sasuke and to find out he's cheating would shatter her world. She could become withdrawn and focus more on her medical ninjutsu as a way to cope.