This is a really disturbing concept. Fanfiction often takes creative liberties, but this seems quite extreme. It could potentially explore themes of betrayal and the darker side of relationships. Maybe the author wants to show how Hermione, despite being a strong character, can be broken down by those she trusts. However, it's important to note that this goes against the general spirit of the original series where friendship is a positive force.
In the fanfiction, Dumbledore might play a crucial role. He is known for his wisdom and care for students. He could detect what's going on with Hermione and use his influence to ensure her safety. He could perhaps arrange for some sort of magical protection or even intervention in her family situation, like counseling for her parents if possible.
She might be initially shocked. After all, she would have trusted her friends a great deal. Then she could become very sad and withdrawn. She might throw herself into her studies even more as a way to cope, trying to distract herself from the pain of losing her friends.
After the initial reactions, Hermione may choose to isolate herself for a while to figure things out. She would use this time to study and research, trying to find a solution to the problem with her friends. She might also look for new allies or resources within the fanfiction world to help her deal with the situation.
She might be initially shocked and hurt. Hermione is a character who values her friendships deeply, so their sudden departure would be a big blow. She could spend some time in denial, not believing that they would actually leave her.
This title immediately makes me think that the fanfiction might be a very emotional and perhaps controversial read. Hermione is a smart and strong character, so the idea of her being abused by her friends is quite a departure from the norm. It could be interesting if the story uses this as a way to show her growth and how she copes with such a difficult situation.
One possible reason could be a misunderstanding. Maybe there was a miscommunication between Hermione and her friends, which led to them leaving her in the fanfiction. For example, if Hermione made a decision without consulting them, they might feel left out and decide to leave.
One possible plot could be that Hermione's friends start believing false rumors about her. For example, they might think she's been stealing potions ingredients for personal gain when in fact she was framed. As a result, they shun her and exclude her from their group activities. This makes Hermione feel isolated and betrayed, and she has to find a way to clear her name and either regain her friends' trust or find new allies.
Harry and Ron would probably be very worried. They'd rush to her side immediately. Harry might use his skills to try and find a way to heal her quickly, while Ron would be freaking out a bit but also trying to be helpful.
Harry and Ron could be there for her. They might notice small signs at first, like Hermione being more jumpy. Then they could offer a safe place for her to talk. For example, in the Gryffindor common room late at night.