In the fanfiction, Naruto and Naruko could start off as strangers who are brought together by the mystery of their Uzumaki bloodline. They might be curious about each other's abilities and start to train together. During this process, they would have small arguments because of their different ways of using the bloodline powers. However, these arguments would actually make them understand each other better. As time passes, they become closer and closer, and the relationship develops from acquaintances to friends, and finally, lovers. Their Uzumaki bloodline would be like a thread that ties them together throughout the development of their relationship.
In such a fanfiction, possible abilities could include enhanced chakra control, like Naruto's already amazing chakra control but perhaps taken to a new level. Maybe there would be a unique form of the Rasengan that combines Naruko's special traits. Another ability could be some sort of advanced sensory perception that is a blend of both their natural talents.
One possible plot could be that Naruto and Naruko (assuming it's an alternate universe where there's a female version of Naruto) discover a new and powerful bloodline ability within their Uzumaki lineage. They might have to train together to master it and then use it to protect the village from a new threat. Maybe it's a bloodline ability that allows them to manipulate time on a small scale, like slowing down an enemy's attack.
It could change the story by making the duo even more powerful. They might be able to take on stronger enemies earlier in the story. For example, they could defeat Orochimaru much more easily with their combined bloodline limits.
One possible plot is that Naruko discovers her vampire bloodline after an encounter with a powerful and ancient vampire. This newfound heritage causes chaos in her life as she is both feared and desired by different factions. Some might want to use her power for evil, while others see her as a key to a greater good. She has to navigate this complex web of relationships while coming to terms with what she is.
One idea could be that Naruto Namikaze and Naruko Uzumaki are partners on a dangerous mission. They start off not getting along well, but as they face various challenges together, they gradually develop a deep bond. For example, they might have to fight a powerful enemy that requires them to combine their unique skills and abilities.
A really interesting plot could be a time - travel fanfiction. Naruto Uchiha (again, with his Uchiha - like characteristics) travels back in time and meets a younger Naruko Uzumaki. He tries to change the future for the better, and in the process, they fall in love. Or perhaps a story where they are in a different world altogether, a world where the ninja clans have different power dynamics. They have to rely on each other to survive and in that process, their love blossoms.
It could make her relationships more complicated. Her friends might be initially scared or distrustful when they find out about her vampire side. However, some might also be intrigued and want to help her control her new powers.
In a fem Naruto Uzumaki bloodline fanfiction, the story could focus on how her bloodline affects her relationships. Since the Uzumaki are known for their strong bonds, as a female Naruto, she could form deep friendships and alliances in a different way. Her bloodline might also attract unwanted attention from villains who want to use her power for their own gain. This could lead to many exciting adventures and battles as she tries to protect herself and those she cares about.
Another plotline could revolve around her being the last of the Uzumaki in a particular region. This would put a lot of pressure on her to preserve the bloodline and its techniques. She could face challenges from other clans who are jealous of the Uzumaki's power or who want to see the bloodline die out. This would lead to intense battles and political intrigue within the ninja world.