He may try to understand Boruto's reasons. Naruto has always been one to look for the good in people. So, even when hurt, he might give Boruto the chance to explain himself. He could say something like 'Boruto, I know you didn't mean it. Let's talk about what's wrong.' He'll be patient and try to resolve the issue rather than getting angry right away.
Naruto could also react with anger. He's not one to just take things lying down. If Sakura hurts him, he might lash out verbally. He could say things like 'I've always been there for you, and this is how you treat me?' expressing his frustration and pain. And then he might storm off, leaving Sakura to realize the impact of her actions.
He might be initially shocked. Naruto is used to thinking of Hana as an ally, so if she hurts him, it would be unexpected. He could immediately try to get some distance to assess the situation and figure out why she did it.
In other fanfics, Naruto might try to understand Sakura's perspective. He's a very forgiving person, so he could give her the benefit of the doubt and try to figure out what made her act in a way that hurt him. He might think that she had her reasons and try to work through it with her.
Naruto may also try to find a way to forgive. Despite the hurt, he has a big heart. He might think about all the good times they had before and try to understand her reasons. However, this doesn't mean he won't be cautious around her in the future. He could give her a second chance but be more guarded, waiting to see if she'll hurt him again.
In some cases, Naruto could be deeply hurt and withdraw from Hinata. He might question their relationship and whether he misjudged her all along. If the hurt is physical, he may also be more cautious around her in future interactions. For example, if she accidentally used a strong jutsu on him during training, he might be hesitant to train with her again without proper precautions.
Macgyver would probably be very worried. He'd quickly assess the situation and try to stop the bleeding if she was bleeding. He'd use his resourcefulness to make a makeshift stretcher or bandage.
When Wu Zhu was filming " Celebrating the Years," he had covered his eyes and relied on his hearing and touch to sense his surroundings. He could use the iron staff to scout the way, or let other characters help him walk. This method of filming could show that Wu Zhu could only sense his surroundings through his hearing and touch. Therefore, Wu Zhu's actors had to rely on their sense of hearing and touch to sense their surroundings while filming, and they had to walk with the help of iron staffs or other characters.