It's likely not a true story. Most often, such titles are part of fictional literature where the plot and characters are created by the author's imagination rather than real-life occurrences.
On April Fool's Day, Sarah received an anonymous love note. She thought it was a real confession. She started to look for the sender. Meanwhile, the person who sent it, David, was just playing a prank. But as he watched Sarah search so earnestly, he started to fall for her. Eventually, he told her the truth and also told her that his prank had turned into real love. They then began their love story.
One big Asian fool story could be about a man who tried to carry a huge bamboo pole through the city gates sideways. He was so focused on getting it through that way that he didn't realize he could simply turn it upright and pass through easily. It shows that sometimes people can be so set in their ways that they miss the simplest solutions.
One April Fool's Day, a man told his friend that there were free concert tickets available at a local store. His friend rushed there, only to find out it was a joke. The friend was initially a bit mad but then they both had a good laugh about it.
Perhaps the shemale in the comics used manipulation, false promises, or played on your emotions to fool you. Maybe the story had unexpected twists that caught you off guard.