An angry cartoon meme usually has exaggerated facial expressions, like wide-open eyes and a scowling mouth. Also, the colors might be bold and intense to convey the anger.
Well, start with a simple shape like a rectangle or oval. Then add sharp corners and lines to show the frown and gritted teeth. Use shading to give it depth and make it look angry.
Well, it could be that someone teased it or it faced some sort of obstacle that made it angry. Sometimes, in cartoons, characters get angry for all sorts of random reasons to add drama and fun to the story.
Often, when cartoon eyes are angry, it's to show a character's strong emotion. It could be because of something that happened in the story or to emphasize their personality. The choice of colors and shading can also contribute to that angry look.
Well, such a character could be very stubborn, always wanting to get her way. She might also have a sharp tongue and use it to taunt others. Her anger could drive her to do really bad things without thinking about the consequences.