I think Itachi has the upper hand. His Sharingan abilities and strategic mind give him a big advantage over Orochimaru. Plus, Orochimaru has always been wary of Itachi's power.
Itachi would likely win. He's incredibly powerful and has shown the ability to outsmart and overpower many strong opponents.
In the manga, Itachi has the upper hand. His Sharingan abilities and strategic mind give him an advantage over Orochimaru. Orochimaru's tricks might not be enough to overcome Itachi's prowess.
Itachi Uchiha would likely win. His Sharingan abilities and strategic mind give him an edge over Orochimaru.
Itachi is the probable winner. His mastery of various jutsus and his intelligence make him a tough opponent for Orochimaru. Orochimaru's obsession with power doesn't necessarily translate to victory against Itachi.
Hard to say for sure. Both Itachi and Sasuke had unique strengths in the manga. Maybe Itachi's experience would give him an edge, or Sasuke's raw power and drive could tip the scales in his favor.
Itachi is likely to win. He's got powerful Sharingan abilities and strategic skills that might give him an edge over Kakashi.
Itachi would likely win. He was a highly skilled and powerful ninja with advanced Sharingan abilities.
It's hard to say for sure. Both Sasuke and Itachi are incredibly powerful, and it could depend on various factors like their skills and strategies at the time.
Itachi is likely to win. He's highly skilled and has powerful techniques that could give him the upper hand.
Itachi would likely win. He's a master strategist and has powerful Sharingan abilities that give him an edge.