In a crossover with 'The O.C.', Ryan and Serena could be an interesting pairing. Ryan's tough - guy exterior and Serena's free - spirit could create a dynamic relationship. Another great pairing could be Blair and Summer in a 'Gossip Girl'/'The O.C.' crossover. Their different styles and personalities would either clash or they could learn from each other. Also, in a crossover with 'Glee', Rachel and Blair could be paired. They both have strong personalities and big dreams in their respective worlds.
Atherton and Jack O'Neill could be an interesting pairing. Atherton from Farscape is a complex character, and Jack is a military man with a lot of experience. Their different outlooks could lead to some great banter and conflict. Another could be Chiana and Sam Carter. Chiana is a resourceful and street - smart character, while Sam is a brilliant scientist. They could learn a lot from each other.
Another good pairing could be Jacob and Thor. Jacob's shape - shifting ability and his connection to nature could be something that Thor respects. They could bond over their physical strength and their loyalty to their respective groups. And Thor could introduce Jacob to the world of Asgardian magic and technology.
Another good pairing could be Spartan Locke and Black Widow. Locke is a skilled and stealthy Spartan, and Black Widow is a master spy. They could work together on covert missions, sharing their skills in combat and infiltration. For example, Locke could provide the muscle and high - tech support while Black Widow uses her espionage skills to gather intelligence.
Morgan from 'Fear the Walking Dead' and Rick from 'The Walking Dead' would be an interesting pairing. Morgan has his unique philosophy on life and death, and Rick is a natural leader. Their different leadership styles could either clash or complement each other in a crossover scenario.
Ash and Red would be an amazing pairing. Red is such a skilled trainer from the Pokemon adventures, and Ash has his own unique style. They could learn a lot from each other. Red could teach Ash some advanced battle strategies, while Ash could show Red how to be more in tune with his Pokemon's emotions.
Akira and Giorno would make an interesting pairing. Akira has his leadership skills and the ability to use Personas, while Giorno has his determination and powerful Stand, Gold Experience. They could learn from each other's sense of justice and different ways of achieving their goals. Akira could teach Giorno about the power of the collective, as the Phantom Thieves work as a team, and Giorno could show Akira how to be more assertive and decisive in his actions.
A rather unexpected but potentially great pairing could be Ashley Williams and Vala Mal Doran. Ashley is a tough and no - nonsense soldier in Mass Effect, and Vala is a wily and resourceful adventurer in Stargate. They could get into all sorts of scrapes together and use their different skills to get out of them. On the other hand, Kaidan Alenko and Jonas Quinn could be paired. Kaidan has biotic powers in Mass Effect, and Jonas has his own unique abilities in Stargate. They could explore how their powers might interact or complement each other in different situations.
Happy from Fairy Tail and Jigglypuff would be an interesting pairing. Happy loves fish and Jigglypuff loves to sing. They could have a comical relationship where Jigglypuff's singing puts everyone to sleep except Happy, who just enjoys the performance. And in times of trouble, Happy could fly Jigglypuff around to safety or to strategic positions in a fight.
One great pairing could be Celty and Uta. Celty is a headless rider with a lot of mystery around her, and Uta is a ghoul with a deep love for art and his own brand of mystery. They could share their knowledge of the underground and the strange things they've seen. Another interesting pair would be Shizuo and Ayato. Shizuo's strength and short - temper against Ayato's rebellious and somewhat violent ghoul nature would lead to some intense confrontations. And finally, Izaya and Nishiki could be paired. Izaya loves to play with people's minds, and Nishiki has his own complex relationship with his ghoul identity and his past actions. Izaya could really mess with Nishiki's head in the crossover.
Iron Man and Ethan Hunt would be an amazing pairing. Iron Man with his high - tech suit and Hunt with his resourcefulness. They could share their knowledge of gadgets and come up with some really cool strategies to defeat the enemy. Another great pairing could be Black Widow and Ilsa Faust. Both are strong female characters with great combat skills and espionage experience. They could work together undercover and take down the bad guys from the inside.