Another plot could be that Naruto travels back in time to the period before the Uchiha massacre. He uses his knowledge of the future to change the course of events. He might befriend the Uchiha members earlier, and by showing them a different path, one of unity and acceptance in the village, he saves the clan from being wiped out.
One possible plot could be that Naruto discovers a hidden prophecy about the Uchiha clan's downfall long before it actually happens. He then uses his influence and his own unique abilities to prevent the events that lead to the clan's massacre. For example, he might find a way to resolve the conflict between the Uchiha and the village leadership without bloodshed.
In some fanfictions, Naruto could learn some long - lost jutsu that has the power to reverse the curse of hatred that plagues the Uchiha clan. He uses this jutsu on Sasuke first, and then they work together to save the rest of the clan from self - destruction. This could involve a lot of character development for both Naruto and Sasuke as they face their inner demons and the history of the Uchiha.
A plotline could involve Naruto finding a hidden power within the Uchiha clan that was overlooked. He uses this power to unite the clan and make them strong enough to resist any threats. Maybe this power is related to an ancient Uchiha technique that Naruto helps to rediscover. He then uses his charisma and leadership skills to convince the Uchiha to work with the village instead of against it.
If Naruto saved the Uchiha clan, the story of the Hidden Leaf Village would be rewritten. The history of the Uchiha's massacre would no longer be a dark stain on the village's past. The Uchiha would contribute their unique skills and abilities to the village's development. For example, their Sharingan abilities could be used for better security or in battles against common enemies. There would also be a change in the relationships between characters. People who were once enemies of the Uchiha might have to learn to work with them.
One plot could be Sarada's search for acceptance within the clan. Since she grew up in a different environment, she may struggle to fit in initially.
One way Naruto could save the Uchiha clan in fanfiction is by using his influence. Naruto is highly respected in the village. He could convince the village elders to re - evaluate their treatment of the Uchiha. He might show them that the Uchiha were being wrongly persecuted and that there was a way to co - exist peacefully. He could also use his power as a Jinchuuriki to protect the Uchiha from any external threats that might be a factor in their downfall.
In some versions of this fanfiction, perhaps the Uchiha Naruto marries is a long - lost relative of Sasuke. This would add an interesting dynamic as Naruto and Sasuke already have a complex relationship. It could also involve Naruto having to prove himself worthy to the Uchiha clan in order to marry into it.
Danzo could be a main antagonist. He was always paranoid about the Uchiha clan's power and was involved in many of the events that led to their downfall. In a fanfiction where Naruto is trying to save the clan, Danzo would likely oppose Naruto's efforts as he sees the Uchiha as a threat to his own power and the village's stability in his own twisted way.
In some fanfictions, Isaribi could be lost in a dangerous, uncharted territory filled with deadly beasts. Naruto, being the hero he is, sets out on a solo mission to find and save her. Along the way, he overcomes various challenges, both physical and mental, and finally reaches Isaribi just in time to protect her from a huge, menacing monster.
Well, one possible interesting plot point could be Sakura using her medical ninjutsu in a unique way to heal the Uchiha members from some sort of affliction that was threatening the clan. Maybe she discovers a new form of chakra control that can reverse the effects of the Sharingan's overuse, which is often a problem in the Uchiha clan.
Obviously, Sakura is one of the main characters as the title implies. She is likely to be the driving force behind the saving of the Uchiha clan.
One possible plotline could be Naruto being adopted into the Uchiha clan early on. He might then learn the unique Uchiha jutsus and secrets at a young age. This could lead to him having a different relationship with Sasuke, perhaps as a brother - like figure within the clan.