If Naruto has leukemia in a fanfiction, his friends' reactions would be complex. For example, Kiba might be angry at the situation, feeling that it's unfair to Naruto. He would try to find ways to make Naruto feel better, like taking him on walks with Akamaru. Rock Lee would be inspired by Naruto's fight against the disease, seeing it as another form of training. Tenten would help by getting any items or herbs that might be useful for Naruto's treatment. And all of them together would form a strong support network for Naruto, constantly reminding him that he's not alone in this fight.
Sakura would be both amazed and a bit worried. Amazed at the new powers Naruto has, but worried about how he got them and if there are any side effects. Sasuke might be a bit jealous at first, as the Sharingan was his clan's special ability, but then he would also see the potential in Naruto's new powers for their common goals. Shikamaru would probably just be intrigued and start thinking about how to use Naruto's new abilities in their team strategies.
Sasuke would likely be a bit more reserved in his reaction. He might see the cybernetics as a potential advantage for Naruto but also as a sign of Naruto relying too much on technology rather than his own natural skills. However, if he saw that the cybernetics made Naruto stronger and more capable of fighting their common enemies, he would probably come to accept it over time.
His reaction would depend on how the betrayal was presented. If it was a sudden revelation, he would be shocked and devastated. He may start to question his own worth, thinking that if his own parents could betray him, what was wrong with him? He could also become more reckless in his actions, not caring about the consequences as much since he felt like he had already lost the most important thing. This new Naruto could also be more empathetic towards the villains in the story, understanding their feelings of being wronged or betrayed in some way.
Sakura would be shocked and heartbroken. She has always seen Naruto as a positive force. She would try to understand what led Naruto to this change and might attempt to use her medical ninjutsu to see if there's some sort of mental or physical ailment causing it. And she would definitely be among the first to oppose Naruto if he starts doing harmful things.
Hinata would be heartbroken. She loves Naruto deeply. Her world would shatter. She might try to find out the truth behind his death, not believing that his friends could do such a thing without a good reason. And she would probably hold a grudge against those involved.
Sasuke would probably be very against it. He has a strong sense of justice and would see this as completely wrong. He might directly confront those who are forcing Naruto into this situation.
His friends like Shikamaru would likely find the whole situation tiresome at first. He'd be thinking 'What a drag, now we have to deal with Naruto and his pacifier.' But then he might start to see the humor in it and use it as a way to tease Naruto in a friendly way. Choji would probably be more sympathetic and offer Naruto some snacks to go with his pacifier, seeing it as something that makes Naruto a bit more vulnerable and in need of comfort.
Sakura would probably be the first to jump into action. As a medical ninja, she'd immediately start examining Naruto and try to figure out the cause of the fever. She might be worried but also very focused on treating him.
Sakura would likely be very concerned. She's a medical ninja, so she'd first check Naruto's physical condition to make sure there's no underlying medical issue causing the panic attack. Then, she'd try to calm him down by speaking softly and reassuringly, reminding him of all the times he's overcome difficulties.
Sakura might be initially suspicious. She is a smart girl and would wonder about the butler's intentions. She might keep a close eye on him to make sure he doesn't harm Naruto in any way.