In some fanfictions, a great plot twist could be that the werewolf Hermione gets to know is actually a long - lost relative of one of her friends. This completely changes the dynamic of their relationship and adds a whole new layer of complexity to the story.
Another interesting plot twist is when the werewolf turns out to be an undercover agent for the Ministry of Magic, but Hermione doesn't find out until much later. It makes the reader question every interaction they had before the revelation. This type of plot twist keeps the readers on their toes and makes the fanfiction more exciting.
A really cool plot twist is when the werewolf she gets to know is not really a werewolf at all, but a wizard under a powerful curse that makes him appear as one. Hermione has to figure out how to break the curse, and in the process, she uncovers a dark conspiracy within the wizarding world that involves some of the most powerful wizards.
Well, one plot twist could be that Hermione's werewolf nature is kept hidden until a crucial moment in the story. Maybe she has been using magic to suppress it all along, but then during a full moon at Hogwarts, she loses control and reveals her true self. This would shock her friends like Harry and Ron, and they would have to figure out how to deal with it while also keeping it a secret from the rest of the school.
A plot twist might be that the werewolf gene behaves differently during the pregnancy. Instead of the usual werewolf transformation problems, it gives Hermione or Draco the ability to communicate with other magical creatures in a unique way. Also, perhaps there is a prophecy related to the baby that no one knew about before the pregnancy. This could put Hermione and Draco in a difficult situation as they try to protect their unborn child from those who might want to use the prophecy for their own gain.
One possible plot twist could be that Hermione gets plastic surgery to go undercover in a wizarding world where appearance is crucial for a mission. Maybe she has to infiltrate a group that only accepts people with a certain look. Another could be that she gets plastic surgery due to some kind of spell gone wrong that affected her appearance and she's trying to reverse it through muggle means as a last resort.
A lesser - known but really good one is 'Hermione and the Werewolf's Tale'. Here, Hermione is assigned a project to study werewolves more closely. Through this, she meets a werewolf who is quite different from what she expected. The fanfiction shows how Hermione overcomes her initial fears and prejudices and forms a strong bond with the werewolf character.
One common plot twist could be that Hermione's makeover is part of a magical experiment gone wrong. For example, a spell meant to enhance her appearance slightly ends up changing her looks drastically in an unexpected way. Another plot twist might be that the makeover is a disguise for a secret mission. Maybe she has to infiltrate a group that only allows a certain 'look' and so she gets a makeover to fit in. And sometimes, the makeover is a result of a bet or a challenge, like she lost a bet to Ron and Harry and has to get a makeover as the consequence, which then leads to all sorts of new adventures and interactions with other characters.
Perhaps a plot twist is that when Hermione is bitten, she gains a special connection to the werewolf pack. Instead of being an outcast, she becomes a sort of mediator between the wizarding world and the werewolves. This causes a stir in both communities as they have to re - evaluate their views on werewolves and those bitten by them.
A great plot twist could be that the love potion Hermione is exposed to actually has a secondary effect. While it initially makes her seem infatuated, it's secretly stealing her magic. As she becomes more and more 'in love', her powers start to wane. Her friends notice the change in her abilities and suspect foul play. They then have to race against time to find out what's really going on and reverse the effects before she loses all her magic.
One possible plot twist could be that Stiles has been a werewolf all along but has been using some sort of magic or potion to suppress his werewolf side. This could be revealed when he is put in a life - or - death situation and his true nature emerges to save the day.
A possible plot twist is that their friendship is initially a ruse. Maybe Pansy is trying to get closer to Hermione to steal some important study notes or secrets for her own academic gain or to help out other Slytherins. However, as time goes on, she actually starts to really care for Hermione and the fake friendship turns into a real one. This would lead to a lot of internal conflict for Pansy as she has to come clean about her initial motives.
A really interesting plot twist could be that Hermione gets pregnant, but then Ron suddenly loses his memory. So he has no idea that they are in a relationship or that she's carrying his child. Hermione then has to not only deal with the pregnancy but also try to help Ron regain his memory. Another plot twist could be that they find out that the baby is part - Veela, which is completely unexpected considering their family backgrounds. This would bring in a whole new set of challenges and cultural differences to deal with. And yet another could be that the Ministry of Magic tries to interfere with their pregnancy for some political reason, creating a conflict between them and the wizarding government.