If Naruto becomes unstable, Sasuke might be one of the first to be affected. Since they have a deep bond, Sasuke would feel responsible to bring Naruto back to his normal state. Sakura, too, would be worried. She might try to use her medical ninjutsu skills to see if there's a physical cause for Naruto's instability and then try to find a solution.
Well, for the younger generation in the village, Naruto is a role model. His instability would be really scary for them. They might start to lose faith in the village's protection. His enemies, on the other hand, would see this as an opportunity. They would try to take advantage of his instability to launch attacks on the village. For his teachers like Kakashi, he would be deeply troubled. He would search for answers, maybe look into old ninja scrolls or consult with other powerful ninjas outside the village to find a way to help Naruto. And his instability could also put a strain on his relationship with Hinata. She would be extremely worried and would do everything she could to support him, which could be difficult if Naruto is in an unresponsive or unpredictable state.
It can create more conflict. His mental instability might make him unpredictable, causing his friends to be unsure how to deal with him. This could lead to internal strife within the group.
It can make characters like Kakashi feel a bit annoyed. Kakashi might think Kurenai is being too overbearing and it could disrupt the normal team dynamics if he also has a role in Naruto's development.
It could make his friends worry a great deal. For example, Sasuke might be concerned about Naruto's well - being and try to reach out to him. This could lead to a new dynamic in their relationship, with Sasuke being more proactive in their friendship.
His friends would be worried. Sakura, for instance, might try to reach out to him and get him to open up. She could be constantly checking on him, bringing him food or just sitting with him in silence, hoping he'll start talking again.
The village elders would be in a state of panic. Naruto was seen as a symbol of hope and power for the village. His departure would mean a significant loss of strength and morale. The younger generation of ninja who looked up to Naruto would also be greatly affected. They might lose their motivation and start to question the values of the village.
If Naruto has a physical disability like a broken arm that doesn't heal properly in fanfiction, his friends like Sasuke and Sakura would need to step in and help him more. Sasuke might be more protective, which could change their dynamic from a competitive one to a more collaborative one. Sakura could use her medical skills to try and find a way to heal him, which would bring them closer. His relationship with his teachers, like Kakashi, would also change as they'd have to adjust their training methods.
His friends would be hurt. They are used to the warm - hearted Naruto, and his coldness would make them feel rejected and confused. They might try to reach out to him but be constantly rebuffed.
His relationship with his sensei, like Kakashi, could become more complex. Kakashi would feel guilty for not being able to protect Naruto from the experiments. And Naruto might start to question Kakashi's ability to keep him safe. This could lead to a strain in their relationship at first, but later they could grow closer as Kakashi helps Naruto recover from the trauma of the experiments.
As for the other Konoha 11 members, they might initially be skeptical. But as they see how Sasuke is changing for the better under Naruto's adoption, they start to include him more in group activities. They come to respect Naruto's decision and see Sasuke in a new light, which gradually strengthens the overall unity among them.
Enemies would definitely be more cautious around Naruto. Those who once underestimated him would now fear his golden chakra. This could lead to some enemies trying to find weaknesses in it. Meanwhile, Naruto's new power might also attract the attention of mysterious characters who want to guide him in using it, which could cause some friction with his existing relationships as he has to decide who to trust.