An OC who is a warrior from a far - off tribe could be interesting. This warrior comes to Talisa's land seeking allies. Talisa, being diplomatic, tries to understand their culture and purpose. They could have a series of interactions where they learn from each other's combat and diplomatic skills.
A simple peasant - turned - messenger OC could interact with Talisa. The OC is often in the castle delivering messages and notices Talisa's kindness towards the servants. They start to have small conversations that gradually develop into a friendship where the OC tells Talisa about the real situations and problems faced by the common folk at the grassroots level.
One possible plot could be that your OC is a healer who befriends Talisa. They meet when Talisa is tending to the wounded in a battle. Your OC has some unique healing skills and together they save many lives. As they spend more time together, they share their different cultures and views on life, and your OC becomes a trusted confidant of Talisa.
Sasuke is also a likely candidate. The OC could try to understand Sasuke's pain and help him find a different path than revenge. Their interactions could be full of tension and deep conversations about power, family, and loyalty.
A group of bandits could interact with the OC. At first, they might try to rob the OC but then realize that the OC has some unique skills that could be useful for them. So, they strike a deal. Also, an elven archer who is very distrustful of humans (including the OC) but gradually warms up as the OC shows respect for the elven culture. And a talking animal, like a fox, that is a bit of a trickster but also has a lot of knowledge about the secrets of the forest in this other world.
Pinkie Pie might also be a good choice. Since Pinkie is already a bit of a wild card herself, her interaction with the Bride of Discord could either result in double the chaos or Pinkie Pie somehow taming the Bride's chaos in her own unique, zany way.
Bellamy could be a great character to pair with an OC. He is a strong leader and has a complex personality. An OC could either be a friend who helps him make better decisions or a love interest who softens his tough exterior.
Temari would be a great addition. She's strong - willed and a skilled shinobi. The OC could have some friendly rivalries or training sessions with her. Also, Baki, as a sensei in Suna, could play a role in mentoring the OC in some Suna - specific jutsu or combat styles. Another interesting character could be the Fourth Kazekage. Even if it's just through flashbacks, his actions and decisions had a huge impact on Suna, and the OC could learn about Suna's history through stories about him.
They could be classmates. For example, if the OC is in Gryffindor, they can study with Harry, Ron, and Hermione, participate in Quidditch practice together, and get into adventures in the Forbidden Forest. Or they could be rivals, like an OC from Slytherin who always tries to outdo Harry in every magical test or duel.
Obviously, the original character (oc) with telepathic abilities would be one of the main characters. This oc could be a human who suddenly discovers their powers and has to navigate the dangerous world of Twilight. There could also be the main characters from the original Twilight series like Edward and Bella. The oc might interact with them in various ways. For example, the oc could use their telepathy to help Bella understand Edward's vampire nature better, or they could be in conflict with Edward because their telepathy reveals things he wants to keep hidden.
Obviously, the main character would be the 18th Targaryen king OC himself. He would be the central figure around which the story revolves. His advisors could also be important characters. Maybe an old, wise maester who has been in the court for years and tries to guide the young king. And of course, his enemies, like a power - hungry lord who wants to usurp the throne.
A character like an OC penguin who is a master of disguise would be really cool. This penguin can transform into any other animal in Madagascar, which is very useful when they need to gather information or infiltrate an enemy's lair. The Penguins of Madagascar are always amazed by this OC's skills and rely on it during their missions.