Perhaps in this fanfiction, Naruto's relationships with others are deeply affected. His friends might try to fill the void left by Kushina. For example, Iruka could become even more of a father figure. Also, Naruto's view of family could be distorted. He might question what it really means to have a family since his own mother left him.
One possible plotline could be Naruto's struggle with abandonment issues. Since Kushina left, Naruto might have a harder time finding his place in the village. He could become more withdrawn and have to fight even harder to prove himself. Another could be the search for Kushina. Naruto might embark on a journey to find out why she left and try to bring her back.
One possible plotline could be that Naruto is somehow transported back in time and has to fight Kushina in a misunderstanding. Maybe he's mistaken for an enemy due to some time - warp magic or jutsu gone wrong. Another could be a scenario where Kushina is controlled by an evil force, and Naruto has to fight her to break the control. Or perhaps it's a sparring match in a dream world where Naruto and Kushina test each other's skills without real harm.
One possible plotline could be that Kushina's survival changes Naruto's upbringing completely. Instead of being an orphan, he grows up with a loving mother. This could lead to him being more confident and less of an outcast in the village at a young age. He might also learn about the Uzumaki clan's secrets earlier from his mother, which could make him a more formidable ninja even faster.
One possible plotline could be that Naruto discovers some long - lost secret about his mother Kushina and decides to leave the village with her to explore this mystery further. Maybe they are on a quest to find some hidden power or knowledge that is related to Kushina's Uzumaki heritage.
One possible reason could be that Kushina was forced to leave Naruto due to some external threat she thought would endanger him more if she stayed. For example, if there were powerful enemies after her and she feared they would use Naruto to get to her.
There might be a very dark and twisted fanfiction like that. It could be that Naruto is tricked into believing that Minato and Kushina are some kind of threat to the village or to his friends. So in a moment of confusion and misinformation, he takes drastic action. But this goes completely against Naruto's character in the original series.
A plotline might involve Kushina being a 'psycho' due to some past trauma. This could lead to her having a hidden agenda within the Hidden Leaf Village. She could be secretly plotting against some of the village leaders while pretending to be a normal citizen. And Naruto, being her son, gets caught in the middle of her schemes and has to figure out how to deal with her and protect the village at the same time. It could also show how Naruto's friends react to this new, darker side of Kushina.
One possible plotline could be Naruto growing up with a sense of deep abandonment and having to face the world alone. This could lead to him having a much more cynical view of life. He might struggle more with controlling the Kyuubi's power as he has no guidance from Kushina. Another aspect could be his relationships with other characters like Iruka or Sasuke being different. Without Kushina's love, he may be more desperate for any form of connection.
A more complex plot could involve time - travel or alternate universes. For example, an alternate universe where the universes of Dragon Ball and Naruto are merged. Goku and Kushina meet under these strange circumstances and have to figure out how to deal with the chaos that ensues while also exploring their new - found feelings for each other. This could involve battles against powerful villains who want to take advantage of the merged universes, and Goku and Kushina would be at the forefront of protecting their new world together.
One possible plotline could be that Naruto is an orphan found by a different ninja clan. He grows up with different values and skills, and his path crosses with Kushina in a completely non - family - related way. For example, they could meet as rivals in a ninja tournament. Another plotline might involve Naruto being from another village entirely and coming to Konoha on a mission where he teams up with Kushina to fight a common enemy. They then form a bond based on mutual respect and shared experiences rather than a family connection.
One plotline could be that Naruto discovers a hidden power within himself that is linked to Kushina's Uzumaki heritage. This power makes him godlike, and he has to learn to control it while also dealing with the memories and emotions related to Kushina that come with it.