One possible plotline could be Naruto feeling extremely lost and having to find his own way to become stronger without their guidance. He might start to question his own worth and abilities, but then he could meet new allies who help him realize his true potential on his own. For example, he could encounter some other outcast ninja who have their own unique skills and together they form a new kind of ninja team that challenges the traditional ways of the ninja world.
Another plot could be that Naruto goes on a journey to find Tsunade and Jiraiya to understand why they abandoned him. Along the way, he discovers secrets about his parents and their relationship with Tsunade and Jiraiya. This could lead to him uncovering a bigger conspiracy in the ninja world that was the reason behind their actions. Maybe it has something to do with an ancient prophecy or a power struggle within the hidden villages.
One possible plotline could be Naruto growing up with a different set of skills influenced by Tsunade. Since Tsunade is known for her medical ninjutsu and super strength, Naruto might have an earlier inclination towards medical skills. He could be trained in a more balanced way between combat and healing. For example, in battles, he not only uses his regular jutsu but also heals his comrades instantly on the spot. Another aspect could be the political influence. Tsunade being an important figure in the village, Naruto might have a different standing in the village hierarchy from the start and face different kinds of challenges related to leadership and decision - making.
One possible plotline could be Naruto growing up with a sense of deep abandonment and having to face the world alone. This could lead to him having a much more cynical view of life. He might struggle more with controlling the Kyuubi's power as he has no guidance from Kushina. Another aspect could be his relationships with other characters like Iruka or Sasuke being different. Without Kushina's love, he may be more desperate for any form of connection.
One possible plotline could be that Naruto's family is in a difficult situation and they believe they can only support his sister. So, Naruto is left on his own. He then has to struggle to survive in the ninja world without the support of his family. He might become more independent and self - reliant, forging his own path.
Another plotline might be that Tsunade is affected by some kind of dark magic or genjutsu that makes her turn against Naruto. Naruto, realizing it's not really Tsunade's fault, still has to fight her to try and break the spell. He could call upon his friends for help, but in the end, it's his determination and his bond with Tsunade that helps him reach her and break the control.
One possible plotline could be that Naruto leaves with Tsunade on a mission to find a rare herb that is said to have the power to heal any wound. Along the way, they face various enemies who also want the herb for their own malicious purposes. Naruto's skills and Tsunade's wisdom would be put to the test as they battle their way through.
Perhaps a plot twist would be that there is some sort of curse associated with Naruto's lineage as their grandson. This curse could be related to the same forces that Tsunade and Jiraiya fought against in their lives. Naruto has to struggle not only with his normal ninja duties but also with this hidden curse. It could manifest in strange ways, like affecting his chakra control or making him a target for certain enemies. On the other hand, it could also be a source of great strength if he can overcome it. And there could be a prophecy related to him being the grandson of Tsunade and Jiraiya that he has to fulfill, which adds another layer of complexity to the story.
One possible plotline could be Naruto growing up on his own, learning survival skills at a very young age. He might become more cynical towards the idea of family. Another could be that he meets someone who becomes like a surrogate family, and through this relationship, he starts to heal his inner wounds. He could also start to search for the reasons why his family abandoned him, leading to a journey of self - discovery.
Perhaps Naruto, after being abandoned by Minato, falls in with a group of outcasts. Together they form a sort of family of their own. Naruto's natural leadership and kind heart start to shine through as he tries to protect this new family. As he uncovers more about his past and Minato, he has to decide whether to forgive his father or hold on to his anger. This internal struggle could be a major part of the fanfiction.
There could be a 'naruto kills jiraiya fanfiction'. It could be based on a time - travel scenario. For example, if Naruto from the future travels back in time and somehow his actions cause a chain of events that lead to Jiraiya's death. Or perhaps there's a dark, alternate universe where Naruto's values are twisted and he sees Jiraiya as an obstacle to his new, malevolent goals and thus kills him.
A great plotline could be the family - like bond that forms between them. Jiraiya, being like a father figure, and Tsunade, like a mother figure, they could have Naruto experience a more stable family life. This could lead to Naruto having different emotional growth. He might become more confident not just in his ninja skills but also in his relationships. Also, they could help Naruto discover more about his parents through their own memories and knowledge.