A plot could involve Otto Octavius trying to atone for his past sins by mentoring Spider - Man in science. This could lead to Spider - Man developing new web - shooter technology or other gadgets. However, Otto's old enemies might target Spider - Man to get to him, creating a dangerous situation for the web - slinger.
Perhaps there's a situation where Otto Octavius' mechanical arms malfunction and start attacking civilians. Spider - Man has to find a way to stop them without hurting Otto. This could be a story about trust and redemption as Spider - Man tries to help Otto regain control while also protecting the city from the chaos.
Perhaps in the fanfiction, Otto Octavius starts mentoring a young scientist. This could lead to him reflecting on his own actions and past mistakes. He could also be involved in a plot where he has to protect his new protégé from other villains in the Spider - Man universe. And it would be interesting to see how his relationship with Spider - Man evolves as he takes on this new role.
A possible plot is that they are both part of a team working on a project to save the city from an environmental disaster. Otto's knowledge of engineering and Mary's understanding of the local ecosystem work hand in hand. As they face challenges and setbacks during the project, they find solace and strength in each other, leading to a romantic relationship. Along the way, they also have to deal with other team members who may not approve of their relationship at first.
In fanfiction, Otto could be a more comical character. Instead of his usual serious and menacing self, he could make mistakes that lead to humorous situations. Like his mechanical arms malfunctioning in a silly way during a fight with Spider - Man. This would add a new dimension to his character.
Maybe in the fanfiction, Spider - Gwen gets lost in the future where Spider - Man 2099 exists. He has to help her get back to her own time while also protecting his own version of New York from the chaos her presence might bring. They could learn from each other's fighting styles and develop a unique bond in the process.
One idea could be exploring the different Spider - People's home universes in more detail. For example, showing what Miles Morales' daily life in his universe was like before becoming Spider - Man. Another could be a team - up between Miles and an older, more experienced Spider - Person from a different universe to face a new and powerful villain.
Perhaps there's a fanfiction where Spider Man and Spider Gwen accidentally swap powers. They have to learn how to use each other's abilities to fight crime. This would lead to some really funny and also challenging situations as they get used to different ways of web - slinging and sensing danger.
In a fanfiction, Spider - Man could be swinging during a big festival in the city. There are so many people and lights that it's hard for him to focus. But then he notices some suspicious activity on one of the floats. He has to swing down carefully, without causing panic among the crowd, and figure out what's going on. It could be a new kind of threat that specifically takes advantage of the chaos of the festival.
One plot idea could be that the Lizard is actually being controlled by an evil scientist who wants to use him to take over the city. Spider - Man has to figure out how to break the control and save his enemy. Another could be a story where the Lizard has a moment of self - awareness and teams up with Spider - Man to stop a greater threat. For example, a group of aliens that are attacking the city and both of them realize they need to work together.
One plot idea could be Spider - Man having to adapt to his paralysis while still trying to protect the city. He could use his intelligence to create new gadgets or strategies that don't rely on his physical abilities. Another idea is that he could inspire other disabled individuals in the city, becoming a symbol of hope for them.
A possible plot could be that Medusa somehow gets transported to Spider - Man's New York City. Spider - Man at first is cautious of her, but then realizes she is not there to cause harm. Together, they try to find a way to send her back to her own place while also dealing with local criminals who are trying to steal her powers. They could also have some comical moments where Spider - Man has to avoid looking directly at Medusa.