Well, one possible plotline could be Naruto having to deal with newfound powers that come with this strange state while trying to keep it a secret from his friends. Another could be how his relationships, like with Sakura or Sasuke, are affected as they notice his different behavior.
In some versions of such fanfiction, Naruto might go on a journey to find a cure or understand the cause of this 'heat' state. This could lead to encounters with new characters or exploring unknown parts of the Naruto world. Also, his training might be affected as he has to cope with the physical and mental changes.
Perhaps a plot where Naruto's determination in the face of some sort of 'heat' - like a difficult situation in the village, and Kakashi is there to guide him. It could involve Naruto learning new jutsus under Kakashi's tutelage while also dealing with his own growing pains.
One possible plotline could be Naruto having to adapt his fighting style. Since he can't hear, he might rely more on his visual senses and his chakra sensing ability. For example, he could learn to read his opponents' lips during battles to anticipate their moves.
One interesting plotline could be Naruto's struggle to adapt to the strict and secretive ways of the ANBU. He's so used to his more open and brash style, so it's a big change. For example, he might have trouble with the stealth aspect at first.
One possible plotline could be a werewolf's struggle to control their 'in heat' instincts while in a human - populated area. They might have to deal with the challenges of hiding their true nature from friends and family.
Another plotline could be Naruto influencing the relationships between characters. He could try to bring Sasuke back to the village much earlier in the timeline, preventing a lot of the pain and conflict that occurred between them. Or he could help his parents, Minato and Kushina, in ways that would change the future of the entire Hidden Leaf village.
One interesting plotline could be Naruto struggling to control his newfound emotions during puberty while also dealing with his ninja training. For example, he might find it harder to focus on his jutsu practice because he's constantly distracted by his changing feelings.
One interesting plotline could be Naruto using his future knowledge to prevent certain tragedies. For example, he might stop the death of his parents. He could also use his knowledge of jutsu to quickly become a much stronger ninja at a younger age and change the power dynamics in the village.
Perhaps there's a plotline where a new member joins the team during this 'in - heat' situation. They have to quickly adapt to the intense conditions and the team dynamics. The new member might have a power related to heat, like the ability to manipulate fire, but they first need to learn how to control it properly within the context of the team and the ongoing heat - related challenges.
One possible plot could be Marceline struggling to control her new vampiric instincts while also dealing with her relationships. For example, how she interacts with her friends like Finn and Jake when she's in this state.
Kakashi Sensei might be in it too. As Naruto's teacher, he would likely be one of the first to suspect something is off and try to help Naruto. Then there are characters like Shikamaru who, with his intelligence, could play a role in either helping Naruto or trying to figure out the mystery behind his state.