His relationship with Sasuke would be very different. Sasuke might be more protective of Naruto as a little girl. He may not see her as the same rival he once did and instead feel a need to safeguard her.
As for Kakashi, he would probably be more lenient with Naruto in this form. He might not push her as hard in training at first because he doesn't want to be too rough on a little girl. But as he realizes that Naruto still has the same determination inside, he would start to train her more seriously while also being more cautious about her well - being.
His relationship with Sasuke could become more complex. Sasuke might be both envious of Naruto's new power and also worried about Naruto losing his humanity in the dragon form. Sakura could be initially scared but then determined to help Naruto control his form, which would strengthen their friendship. His relationship with Kakashi would change as Kakashi would now have to mentor Naruto in a different way, guiding him to use his dragon powers for good and not let them consume him.
Well, with Sasuke, their relationship would become more of a protective - protectee one. Sasuke, who usually has a rivalry with Naruto, would now feel responsible for protecting this baby Naruto. With Sakura, she would be more motherly towards him. She might be the one constantly fussing over him, making sure he's clean and fed.
If Sakura turns into a little girl in the fanfiction, her relationship with Naruto would be very different. Naruto would probably take on a more dominant role in their friendship. He'd be the one making decisions for her and guiding her. Her relationship with her rivals might also change. For example, other female ninjas who were once her competitors might now see her as less of a threat in her little - girl form and might even try to befriend her. And her relationship with her sensei, Kakashi, would be more like a student - teacher relationship where he has to teach her from the very basics again, which would create a different dynamic compared to their previous relationship.
His relationship with Naruto might change. Naruto could be more protective of Kakashi as a girl. He might see her in a different light, like an older sister figure. With Sasuke, there could be some initial awkwardness. Sasuke, who is used to Kakashi as a male, might not know how to interact with him as a girl at first. And with Sakura, they could form a closer bond as girls, sharing things that only females in the ninja world might understand.
His relationship with Mary Jane would become very different. Instead of a romantic interest in the traditional sense, they could become more like sisters or best friends. Mary Jane might help the girl - Spiderman adjust to her new identity.
His relationship with Naruto would likely change. Naruto might be more protective of Neji as a girl, seeing her as more vulnerable. He could also be a bit more awkward around her at first. With Hinata, they might become closer as girls and share different kinds of secrets. And his former male rivals might either be overly competitive in a different way or start to develop feelings for him, which would create a very different dynamic.
Well, with Kakashi, he might be more cautious in how he trains Sasuke. As a girl, Kakashi might have to consider different aspects of training, like physical limitations that might come with the female form. His relationship with his clan members, if they were still around, could also be different. They might have different expectations of a female Sasuke. And when it comes to the other male ninja in the village, some might be attracted to him, which would create some awkward or interesting situations.
As for Naruto, he would probably find it hilarious at first. But then he'd realize that Kiba is still his friend and needs help. Naruto might try to come up with some crazy plan to turn Kiba back, like using his shadow clones to search for a cure or something equally zany.
His relationship with Sasuke would definitely change. Sasuke might be initially shocked and confused. He might see Naruto in a new light, not just as a rival but also as someone he needs to protect. Their dynamic could shift from pure rivalry to a more complex relationship with new emotions involved.
Harry's relationship with Lupin would be very interesting. Lupin, being a werewolf himself, could act as a mentor to Harry. He could teach Harry how to control his werewolf side better. And this shared experience could bring them closer together. But at the same time, Harry might feel a sense of resentment towards Lupin, thinking that Lupin could have prevented his transformation in some way.