Well, perhaps there's a plot where the body swap is part of a villain's plan. The wonder girls have to figure out how to function in each other's bodies while also trying to thwart the villain's scheme. They might initially struggle with using each other's powers or fitting into their social circles, but eventually they use their new perspectives to their advantage.
One interesting plot could be Superman swapping bodies with a normal human. The human then has to deal with Superman's powers while Superman experiences what it's like to be an ordinary person. He might struggle with things like paying bills or getting to work on time in the human's body.
One interesting plot could be that Ladybug and Chat Noir swap bodies. They then have to figure out how to use each other's powers effectively while also keeping their identities a secret from their enemies. It adds a whole new layer of comedy and confusion to their fight against Hawk Moth.
One interesting plot could be that Black Widow swaps bodies with a regular civilian. The civilian suddenly has to deal with all of Black Widow's skills and enemies. It would be a comical yet dangerous situation as they fumble through Black Widow's dangerous life. Another plot could be a body swap between Black Widow and another superhero. They have to adapt to each other's powers and relationships. For example, if she swapped with Captain America, she'd have to deal with his leadership role and he'd have to handle her stealthy and more morally ambiguous world.
One interesting plot could be that Ash, now in Bonnie's body, has to deal with the different social interactions that Bonnie usually has. For example, he might struggle to interact with Bonnie's friends in the way she does. Another plot could be Bonnie, in Ash's body, trying to handle Ash's Pokémon battles. She might use different strategies that surprise everyone. And a third plot could be them trying to find a way to swap back while also learning more about each other's lives.
Another plot could be that the body swap was caused by a strange jutsu gone wrong. In the process of trying to fix it, they end up learning more about each other. Naruto could understand Ino's insecurities better, and Ino could see Naruto's determination and the weight of his responsibilities more clearly. This new - found understanding could change their relationship for the better even after they swap back.
A plot could involve them trying to reverse the body swap. They might search through the library, looking for ancient spells or potions that could fix their situation. Along the way, they'd learn more about each other's insecurities and strengths. Maybe Harry realizes how much Hermione has to put up with in terms of the expectations of being the brightest witch of their age, and Hermione understands the weight of Harry's destiny on his shoulders.
Obviously, the wonder girls themselves are the main characters involved. They could be from different teams or generations of wonder girls.
A frequent plot in body swap teen girl stories is accidental body swaps due to some magical or scientific mishap. For example, a science experiment gone wrong or a magic spell from an old book. Then there's the plot where the teen girl swaps bodies with her enemy. This forces them to see life from each other's perspective, leading to a change in their relationship, from hatred to understanding.
One interesting plot could be that Ash, now in May's body, tries to enter a Pokemon Contest. He has to quickly learn the skills and grace that May has, like how to style the Pokemon in a more appealing way for the judges. Meanwhile, May in Ash's body decides to enter a Gym battle. She struggles with Ash's more straightforward and battle - focused approach compared to her Contest strategies.
One interesting plot could be two female officers swapping bodies and having to deal with each other's daily tasks and relationships. For example, a science officer suddenly in the body of a security officer has to handle combat training and security protocols she's not used to.