One possible plot could be that Hermione, as a Lycan, struggles to hide her identity within the Hogwarts community. Fleur, being perceptive, might notice something off about Hermione. Maybe Hermione is afraid of being discovered and ostracized, while Fleur, having her own experiences with being different (as a Veela), tries to help Hermione come to terms with her new lycanthropy. They could form a strong bond as they both deal with the challenges of being 'other' in the wizarding world.
Hermione's relationship with Harry and Ron would likely become more strained. They might be a bit afraid of her at first, not knowing how to deal with her new lycanthropy. However, as true friends, they would eventually try to understand and support her. With other Hogwarts students, she could face discrimination or fear from some, while others might be curious or sympathetic. Her relationship with teachers would also be different. Some, like Professor Snape, might use it as an excuse to be even harsher on her, while others, like Professor Lupin (who is also a werewolf), could be a source of guidance.
One possible plot could be a story set during a Triwizard Tournament - related event. Maybe Fleur and Hermione are forced to work together in a dangerous task and during a moment of panic or urgency, Fleur straddles Hermione to protect her from some sort of threat. And from there, a new bond forms between them.
Well, it could start with Hermione realizing her deep feelings for Fleur. Maybe she plans a very elaborate and romantic proposal. She might choose a special place like the Hogwarts grounds under a full moon. Fleur could be initially shocked but then really touched by Hermione's boldness.
Perhaps the plot could involve a love triangle. There could be another character, like Viktor Krum, who still has feelings for Hermione and is jealous of her relationship with Fleur. This would add drama and tension to the story. Also, Fleur's family might not approve of Hermione, leading to more conflict.
One possibility could be a situation where Fleur is under the influence of a dark spell. Maybe she's been hexed to do this to Hermione. In the fanfiction world, this could be a lead - up to a rescue mission by Harry and Ron. They would have to figure out how to break the spell on Fleur and free Hermione.
The plot could involve Hermione and Fleur having to adapt to a new, sixth - type of magical environment. Maybe they are sent on a special mission in a realm where the rules of magic are different. For example, they might find that their usual spells don't work as expected and have to learn new ones quickly to survive.
One possible plot development could be that Fleur is initially shocked but then realizes her own feelings for Hermione have been growing. They might face some opposition from their friends or families who don't understand their relationship at first. But through their love and determination, they gradually make others accept their union.
Well, it could develop into a story of deep friendship. Maybe Fleur was trying to comfort Hermione during a difficult time. They might start sharing their secrets and fears, and through this physical closeness, a strong bond of sisterhood could form.
Another possibility is that Fleur, in a bid to gain more influence in the magical world, uses Hermione's research on some ancient magic without permission. When Hermione finds out, she realizes Fleur has been using her all along, and this is the ultimate betrayal. Hermione then has to find a way to expose Fleur's actions and clear her own name.
Well, it could be a story about a deep emotional moment between Fleur and Hermione. Maybe they are in a situation where they are comforting each other or having a very intense conversation. It might also be part of a magical adventure where they are in a dangerous situation and this physical closeness is a result of trying to protect each other.