You could write a fanfiction where Spider - Man has to deal with a new type of symbiote. This symbiote is different from Venom and is much more powerful and dangerous. It starts infecting other people in the city, turning them into mindless minions. Spider - Man has to find a way to stop the spread of the symbiote and also figure out who created it and why.
A great plot for Amazing Spider - Man fanfiction could be a time - travel story. Spider - Man could be sent back in time to the era when his powers first emerged. He could then use his knowledge of the future to prevent some of the tragedies that occurred in his past, like the death of Uncle Ben. Or, he could be sent to a future where New York has become a dystopia, and he has to find a way to fix it and return to his own time.
Maybe in the fanfiction, Spider - Man discovers a secret connection between his powers and an ancient Asgardian artifact. The Avengers, especially Thor, would be intrigued. They then embark on a journey to figure out how this connection could either save or endanger the world. Spider - Man would have to balance his normal life and this new discovery with the Avengers.
One idea could be exploring a new villain that is created from a scientific experiment gone wrong in Oscorp. This villain could have powers related to electricity and pose a new threat to Spider - Man.
One plot idea could be that Gwen discovers a new superpower that she has to learn to control, and Peter helps her through the process. This could add a new dynamic to their relationship as they both have different powers and ways of handling them.
A crossover with the Avengers is also great. Picture Spider - Man having to prove himself to the more established heroes like Iron Man and Captain America. He could bring his unique street - level hero skills to a big - scale Avengers mission.
Maybe Spider - Man discovers a new threat that the Avengers have overlooked. He then tries to convince them of the danger, facing skepticism at first but eventually winning them over with his tenacity and evidence. For example, he could find a hidden group of villains planning to use a new type of technology to take over the world.
A plot could involve Harry getting powers as well, not just from the Goblin formula but in a different way related to some Oscorp experiment. He and Peter then have to figure out how to control their powers together and face a new supervillain created by Oscorp's misdeeds. It would add a new dynamic to their relationship as they both struggle with their newfound abilities.
One idea could be Mary Jane starting her own investigative journalism project related to Spider - Man's enemies. This would put her in danger and force Spider - Man to protect her while also trying to keep his identity a secret from her new inquiries.
One idea could be exploring the different Spider - People's home universes in more detail. For example, showing what Miles Morales' daily life in his universe was like before becoming Spider - Man. Another could be a team - up between Miles and an older, more experienced Spider - Person from a different universe to face a new and powerful villain.
Perhaps there's a fanfiction where Spider Man and Spider Gwen accidentally swap powers. They have to learn how to use each other's abilities to fight crime. This would lead to some really funny and also challenging situations as they get used to different ways of web - slinging and sensing danger.
No one knows for sure yet. But it could involve new villains and more exciting adventures for Spider-Man.