He could use his chakra control to his advantage. For instance, if Orochimaru is trying to inject something into him or perform some sort of chakra - based torture, Naruto could try to disrupt it with his own chakra. Also, Naruto's ability to create shadow clones could be used in a strategic way. He could send out clones to distract Orochimaru while he tries to find a way to escape or counter - attack.
Naruto might resist through his strong willpower. He has always been determined, and this would not change even under torture. He could keep thinking about his friends in the Leaf Village and his goal of becoming Hokage, which gives him the strength to endure.
Naruto may resist by relying on the Nine - Tails' chakra. Even though it's a dangerous power, in a desperate situation like being tortured by Orochimaru, he might be forced to tap into it. The Nine - Tails' raw power could give him the boost he needs to break free from Orochimaru's restraints and fight back. Moreover, Naruto's experience in facing difficult situations and his growth as a ninja over time would also contribute to his resistance.
In some fanfics, Naruto might use his new and powerful jutsu that he has mastered over time. Maybe he combines his Sage Mode with the power of the Nine - Tails in a unique way that Orochimaru can't counter. For example, he could use the Nine - Tails' chakra to enhance the range and power of his Sage Mode attacks, and then catch Orochimaru off - guard.
Well, perhaps in the fanfic, Orochimaru tortures Naruto as a form of revenge against the Leaf Village. He might use his various snake - related jutsu to cause pain and harm to Naruto. For example, he could make snakes constrict Naruto, slowly squeezing the life out of him while also injecting him with some sort of venom that causes excruciating pain. And all this while, Naruto is trying to find a way to break free and defeat Orochimaru, relying on his inner strength and the memories of his friends and his training.
Well, it could make Naruto a much darker character. Instead of his usual optimistic self, he might be filled with vengeance. This would change the dynamics of his relationships. His friends would have to deal with this new, brooding Naruto. Also, it might slow down his progress in becoming a stronger ninja as he has to first deal with the trauma of the torture.
It makes Naruto more complex. Instead of just being the energetic and determined ninja we know, he has a darker side. His tortured past can add depth to his character, making him more relatable as he battles with things like self - doubt and fear.
He could develop post - traumatic stress disorder (PTSD). Flashbacks of the torture might haunt him during battles or normal daily activities. This would not only affect his performance as a ninja but also his personal relationships. Naruto might become withdrawn as a result of the torture. He might isolate himself from his friends and the village in an attempt to protect them from any potential harm that could come his way because of his association with Orochimaru through the torture. This isolation would further damage his mental state as he thrives on the support and friendship of those around him.
Well, in some versions, Naruto might use his new and improved Rasengan techniques. He could have combined it with his Sage Mode powers to overpower Orochimaru. Maybe he also uses his quick thinking and the element of surprise, since Orochimaru is always so full of his own schemes.
Naruto could develop a new sense of determination. He might be determined to not let Orochimaru's experiments define him. Instead, he could use what has happened as a motivation to become stronger in his own way. He may also start to study more about the type of experiments Orochimaru was doing, not to replicate them, but to find ways to counter any future threats related to that kind of science.
In a fanfic where Orochimaru kills Naruto, the plot would take a very different direction. Naruto was the Jinchuriki of the Nine - Tails, and his death would mean the Nine - Tails' power is lost. Orochimaru might try to take over Konoha or use Naruto's death to gain some other advantage. The other ninja villages might see Konoha as weak and attack. His friends would have to deal with the grief and might turn to different paths, some perhaps darker in their search for meaning after such a loss.
It depends on the specific fanfic. Some authors might come up with this plot twist to explore different character motivations and conflicts. In others, it might not be the case at all.
Naruto could also use his chakra to resist. Since he has the Nine - Tails' chakra at his disposal, he might be able to disrupt the experiments. For example, he could flare up his chakra in a way that makes it difficult for Madara to continue with the procedures. Additionally, Naruto has learned various ninja techniques over the years, and he could potentially use them to counteract the effects of the experiments, like using shadow clones to create distractions or using rasengan - like attacks to break free from any devices used in the experiments.