Snape would likely be shocked and then enraged. Harry is supposed to be the hero of the wizarding world, and seeing him drunk would be a huge disappointment. He would most likely drag Harry to his office, lecture him about propriety and the expectations placed on him as a wizard, and probably assign some form of punishment like a long detention. But as he observes Harry more closely during this time, he might start to wonder what drove Harry to this and if there are deeper issues that need to be addressed.
Hermione would likely be a mix of disappointed and worried. Disappointed because Harry is usually responsible, and worried because she cares about him. So she'd probably try to figure out why he got drunk in the first place.
Snape would likely be angry at first. Harry has always been a source of trouble in his eyes, and running away would just add to that perception. He might mutter some sarcastic remarks under his breath about Potter's irresponsibility.
He might be initially startled. Snape is used to seeing Hermione as a strong - willed and confident student. So seeing her crying could catch him off - guard. But then he might quickly put on his usual cold facade and ask her curtly what's wrong.
He would be intrigued and eager to read it.
He'd probably be annoyed. Snape is a serious wizard and he might think fanfiction is a silly Muggle - influenced concept.
Snape's reaction could be quite mixed. On one hand, he might be angry at Dumbledore for not doing more if he knew about the abuse. He may also feel a strange sort of empathy towards Harry. After all, Snape himself had a difficult childhood. So, he could start to be a bit more lenient with Harry in his classes and try to subtly offer support.
Well, Snape has always had a complex relationship with Harry. When he finds Harry cutting himself in this fanfiction, he might be angry at first, thinking it's a sign of weakness. But then, as he realizes the depth of Harry's pain, he could soften. He might start to see Harry more as a troubled child rather than just James Potter's son. Snape could use his knowledge of potions to create something to heal the physical wounds and also try to offer some form of emotional support, albeit in his own gruff way.
Harry would probably be quite startled at first. The idea of Sirius and Remus in a relationship as depicted in the fanfiction photos is not something he's ever considered. But as he looks at the photos more, he could become more understanding. He's used to different magical concepts, and this could be just another one for him to wrap his head around. He might even feel a sense of pride that his father's friends were so interesting that fans created such elaborate stories and photos about them.
He'd probably be shocked. I mean, a tank is so out of place in the Naruto world. He might be scared too, not knowing what this huge, metal thing can do.
Harry would probably be very confused at first. He's so used to Snape's animosity towards him that when Snape forgets who he is, it would be a complete shock. He might also be a bit suspicious, thinking it's some sort of trick. But as time goes on, he could start to feel a bit of pity for Snape, especially if Snape seems lost or confused without his memories of Harry.