I think his friends' reactions would vary. Naruto's closest friends like Shikamaru and Kiba would quickly realize that they need to support Naruto. They would see that despite the strange new form, it's still Naruto. Sakura would be more emotional, she might cry at first but then pull herself together to help. And Sasuke, he would probably see it as an opportunity for Naruto to gain more power, but also be cautious in case the Titan form has any negative effects on Naruto's mind.
His friends' reactions would be mixed. Shikamaru would be like 'This is such a drag.' But he'd also start thinking of strategies to deal with the situation. Ino would be all about helping Naruto with his new look, like suggesting new outfits that would suit a fox girl. Choji would be more focused on making sure Naruto is still the same person inside. He'd offer Naruto his snacks to cheer him up. And Hinata would be blushing a lot, but also be very supportive, saying things like 'Naruto - kun, you look... different, but you're still you.'
Sakura might be initially shocked and a bit jealous at how cute Naruto - as - a - girl is. Sasuke would probably be confused at first but then act indifferent. Kakashi would be his usual calm self, but might crack a few jokes about Naruto's new look.
At first, his friends would be in disbelief. But then, they would start to adapt. Dawn might see it as an opportunity to study a Pokémon from a different perspective. Gary could be both amused and intrigued, and might offer some scientific theories on how it happened. Overall, they would all be concerned for Ash's well - being and work together to either help him get back to normal or help him thrive in his new form.
His friends would be very shocked at first. Misty might be a bit worried and try to find a way to turn him back quickly. Brock, on the other hand, would be more curious and start observing Ash - as - Pikachu to see how his behavior has changed. His Pokémon friends would also be confused. Pikachu himself might be both excited to have a 'Pikachu - like' friend but also a bit sad that his trainer is in this strange state.
Sakura might be initially shocked. But being a good friend, she would quickly try to understand what happened to Naruto. She could offer to help him find a way to change back or support him in dealing with the new form. Sasuke, on the other hand, might be more aloof at first. He would see Naruto's transformation as a sign of weakness, but as time passes and Naruto proves his strength in the new form, Sasuke might start to respect him again.
Ron would probably be both shocked and a bit awestruck at first. He might make some typical Ron - like jokes to ease the tension, like 'Blimey, Harry, you're a dragon! At least you'll be good for scaring off Snape now!'. But deep down, he'd be worried and determined to help Harry get back to normal.
His friends would be quite shocked. Neville might be a bit scared at first, thinking it's some new dark magic. But then they'd all come together. Ginny would probably be the one to try and comfort 'cat - Harry' by giving him some fish or milk, thinking that's what cats like. And they'd all be determined to get him back to normal as soon as possible.
Sam would probably be really intrigued. She might see it as a cool new form for Danny and would be eager to learn more about how it affects his powers. Tucker, on the other hand, would likely be more concerned about how to reverse it at first. But once he realizes that Danny can still do some cool things as a mermaid, he'd be excited too.
His friends from Team 7, like Kakashi, would feel responsible for Naruto's situation. Kakashi would likely use his resources to find a proper shelter for Naruto. Shikamaru and the others might come together to form a sort of support group for Naruto. They would pool their resources, like money and food, and also try to cheer him up by sharing stories and jokes.
His parents might be really confused at first. They've been hunting ghosts, and suddenly their son is a baby again. They'd probably be worried about his well - being and try to figure out what happened using their scientific knowledge. Jazz, his sister, would likely be very protective. She'd take on a more motherly role, making sure Danny is fed, clean, and safe.