Kakashi might also play a big role. As Naruto's former teacher, he would be both happy and cautious about Naruto's return. He could offer his wisdom and guidance as Naruto adjusts to his new life. Also, Sakura would be there. She might be overjoyed at first, but then also be concerned about the implications of Naruto's resurrection. She could use her medical skills to check on Naruto's condition and also fight alongside him in new battles.
Obviously, Naruto is the central character. But often, his friends like Sasuke, Sakura, and Kakashi are also involved. Sasuke might be there to have some sort of reunion or conflict with Naruto. Sakura could be the one to heal Naruto if he comes back injured. And Kakashi, as Naruto's former teacher, would be there to welcome him back or assess his new abilities.
Sasuke would definitely be one of the main characters to interact with Naruto. Sasuke might be initially skeptical or even jealous of Naruto's new powers as a goddess. But as they are long - time rivals and friends, they would work together. Sakura could also play an important role. She might be in awe of Naruto's transformation at first and then try to help him control his powers. Kakashi too would be involved, acting as a mentor figure, guiding Naruto on how to use his new - found goddess - like abilities in a way that benefits the village and doesn't cause too much disruption.
Kakashi could also play a role. He has been Naruto's mentor for a long time. So, he might have some mixed feelings about Itachi adopting Naruto. He could be suspicious of Itachi's motives at first but then gradually come to understand Itachi's positive influence on Naruto. Their interactions could be really fun to read about, especially when Kakashi tries to give Itachi some advice on how to handle Naruto's wild nature.
Obviously, Nagato himself would be the main character interacting with Naruto. He would be like a mentor or a guardian figure in Naruto's life.
In this fanfiction, Naruto would interact with a variety of characters. First, his old friends like Choji and Kiba. They have been through a lot together and would support Naruto in the war. Then there are the leaders of the different ninja villages. Naruto might meet with the Raikage or the Mizukage. His interactions with them could range from tense negotiations to forming alliances. And don't forget about Hinata. Her support for Naruto could be a source of strength for him during the difficult times of war.
Anko might also be involved in the story. She has her own unique relationship with Yugao and could potentially interact with Naruto. Maybe she gives Naruto some tough love or challenges him in a way that Yugao's teaching methods don't cover. And of course, Iruka sensei could also show up to check on Naruto's progress and have some interactions with both Naruto and Yugao.
Obviously, Naruto himself is a main character. He will be interacting with the Kyuubi. Since the Kyuubi is a powerful and sentient entity within Naruto, their interactions could be intense. Naruto might also encounter other ninja who have knowledge about the Kyuubi. For example, Jiraiya. Jiraiya, being Naruto's mentor, might appear to give advice on how to handle the situation with the Kyuubi. He could share some of his own research and experiences related to the tailed beasts.
Kakashi could play an important role. As Naruto's former teacher, he would surely want to help Naruto understand and control the Caged Bird Seal. He could use his knowledge and experience to guide Naruto. Another character could be Jiraiya. Even if he's not alive in the original story at a certain point, in the fanfiction, he might return as a spirit or something to give Naruto advice about the seal.
Sasuke would definitely be one of the main characters to interact with Naruto. Their relationship has always been complex, and with Naruto as a girl, it could become even more so. Sakura would also interact a lot. She might be both jealous and intrigued by Naruto's new form. Kakashi too, as Naruto's mentor, would have to adjust to this change and guide 'her' in a different way perhaps.
Jiraiya could also be one of the main characters. He was Naruto's mentor and had a connection with Kushina's family. He could play a role in helping them adjust to the time travel and also use their knowledge to his advantage in some ways, like getting intel on future threats.