Well, his relationship with Bruce Banner could be affected too. Banner might be a bit afraid that Loki's condition could lead to some sort of outburst that could trigger the Hulk. But at the same time, Banner's scientific mind might also be intrigued. And in terms of Loki's relationship with Clint Barton, Clint might be on high alert, thinking Loki could use his condition to his advantage, but over time, he could come to realize that Loki is just as much a victim of this as anyone.
Loki's relationship with Tony Stark could change in an interesting way. Stark, being the curious and scientific type, might try to find a scientific explanation for Loki's condition. This could lead to some banter and a strange sort of friendship. And as for his relationship with Steve Rogers, Steve might initially be distrustful but then see Loki's vulnerability and try to be more empathetic.
His relationship with Thor would likely become more strained. Thor might not understand what's happening to Loki at first and think he's up to some new scheme. With the other Avengers, Loki might become more withdrawn as he tries to deal with his situation privately.
If Kakashi goes back in time, his relationship with Rin would be complex. He might try to protect her more, which could lead to a different dynamic between them. He would be more aware of the threats she faces and could be more proactive in her safety. With Guy, he could be a better friend from the start. He could join Guy in his challenges and competitions more often, strengthening their rivalry - friendship. And when it comes to the Third Hokage, Kakashi could offer more insights based on his future knowledge. This might make the Third Hokage rely on him more, and Kakashi could become a more important figure in the village at an earlier stage.
Thor's relationship with Loki would likely become more complex. He'd be glad his brother is being cared for but also worried about Loki's true intentions. The Avengers, like Tony, might start to see Loki as more than just a villain. They could develop a begrudging respect for his intelligence. For Loki, he might start to feel a sense of belonging, which is something he's never really had. This could soften his attitude towards the Avengers.
If Peter was adopted by the Avengers, his relationship with Wanda Maximoff could be quite special. Wanda could help Peter understand and control his emotions better, especially when he's under stress during battles. Peter could also befriend Vision, and together they could explore the boundaries of science and magic. The Avengers would start to see Peter as a full - fledged member of the family. They would be more protective of him, and Peter would feel a stronger sense of belonging. His relationships would no longer be just about superhero partnerships but would be about real family connections. For example, they would celebrate holidays together and have family - style dinners, which would strengthen their bonds even more.
Well, Naruto's relationship with his male friends would take on a new dynamic. For example, Shikamaru might be less dismissive of 'male' Naruto as he might expect different behavior from a boy. Naruto could also get closer to some of the more reserved male characters who usually keep their distance from girls. On the other hand, his relationship with female characters like Ino could become more complex. Ino might be intrigued by this new 'boy' in town and try to figure out what makes him different. And Naruto would have to constantly balance his real self and his pretend self in all these relationships.
With Kakashi, Naruto's relationship would also shift. Kakashi has had experience with the Sharingan and knows about powerful dojutsu. He would be both amazed and a bit worried about Naruto having the Rinnegan. He might try to mentor Naruto more intensively to make sure he uses it for good and doesn't let the power corrupt him. Naruto would look up to Kakashi even more as he tries to learn about his new power from Kakashi's knowledge.
His relationship with Jiraiya would be different. Jiraiya trained Minato, but with Naruto replacing Minato, Jiraiya might train Naruto even more intensively from an earlier age. Naruto would also probably be more open with Jiraiya about his feelings and plans, as he's not as reserved as Minato.
His relationship with Sasuke would be extremely complex. Sasuke, who has his own vendetta against the shinobi world, might initially be suspicious of Naruto's new role. But Naruto, as the Akatsuki leader, would try to convince Sasuke to join him in his new vision for the organization. It could be a love - hate relationship where they constantly butt heads but also understand each other on a deeper level.
His relationship with Sasuke would be very different. Instead of being rivals, they might become more like comrades or even brothers in arms, as Itachi and Sasuke were related. Naruto would probably be more understanding of Sasuke's thirst for power and revenge, and might try to guide him in a more Itachi - like way. With Sakura, Naruto might become more distant, as Itachi was not very close to female characters in the original story. And with his other friends like Shikamaru or Kiba, Naruto would likely be more reserved and less of the loud, exuberant self they knew, which could cause some confusion and concern among them.
When it comes to his friends like Shikamaru and Choji, Naruto might distance himself from them. Zabuza is a loner, and being raised by him, Naruto could start to prefer solitude. He might not value the group dynamic as much as he does in the original story and instead focus on his own strength and survival skills.
His relationship with Sasuke would be really interesting. Instead of Sasuke being the only one with the Sharingan, Naruto now has it too. Sasuke might feel a mix of envy and camaraderie. Envy because Naruto has something that was so much a part of his identity, and camaraderie because they now share a powerful ability.