Dante is a very likely character. His flamboyant and confident personality would make for an interesting contrast in the MLP world. He could be the one who brings a different kind of action and chaos to the usually peaceful pony lands.
Vergil would also be a great addition. His more brooding and power - hungry nature could create a lot of tension. Maybe he would be on a quest for some sort of power in the MLP universe that the ponies have to stop him from obtaining.
A powerful ancient demon that has been sealed away for centuries could be a great villain. This demon could have the power to manipulate time and space, which would make it a formidable foe for both Dante and Bayonetta. It could be awakened by some dark magic ritual gone wrong in both of their worlds, and its goal could be to merge the two worlds into a chaotic realm of darkness where it can reign supreme.
Well, one interesting concept could be the fusion of the dark and edgy style of Devil May Cry with the colorful and magical world of My Little Pony. Maybe it involves characters from Devil May Cry having to adapt to the more positive and harmonious environment of Equestria. For example, Dante might find himself in a situation where he has to use his combat skills in a non - violent way to solve problems in Ponyville.
Lady is quite popular too. She's a strong female character who can hold her own in the demon - filled world of Devil May Cry. Her relationship with Dante, whether it's a friendship or something more, often gets explored in fanfiction.
The Marker in Dead Space is also likely to be a key element in a crossover fanfic. It has such a powerful and mysterious presence in the Dead Space universe. In a crossover with a horror - mystery series, the Marker could be the source of all the strange happenings, and characters from both universes would have to figure out how to deal with it or stop its influence.
In the 'Devil May Cry' story, Dante is the central figure. He's a badass with his red coat and dual - wielding style. Then there's Vergil. Vergil is Dante's brother, and they share a common heritage but different outlooks. Vergil is often more focused on power. Lady, as mentioned before, is a strong female character. She has her own reasons for hunting demons, and her presence adds another dimension to the story. There are also other characters like Trish who play important roles at different points in the story.
The main character is Dante. He is a half - demon, half - human and is the central figure in the story. He has incredible combat skills.
Dante is surely one of the main characters.
It's likely Alucard. His vampiric powers are extremely potent. He can regenerate from almost any injury, has superhuman strength and speed, and can even manipulate shadows. In a crossover, he could potentially overpower many of the Devil May Cry characters, especially if he has the element of surprise.
Definitely Commander Shepard from Mass Effect. He/She is the central character in Mass Effect and would be a natural fit to interact with XCOM forces. Also, XCOM's Central Officer or top - ranking soldiers could be prominent. They could be the ones making decisions on how to deal with Mass Effect threats or form alliances.
Vergil and Lady. Vergil is a complex character, and Lady has a no - nonsense attitude. During the holiday, they might end up in a corner together. Lady could try to understand Vergil's motives better, especially after his return. She might ask him why he chose the path he did, and Vergil could open up a bit about his inner turmoil and his desire to protect his family in his own way.