Some in the wizarding world might be shocked. Since their relationship was unexpected in the first place, their divorce could be seen as yet another scandal. Pure - blood families might use it as an example of why pure - bloods and Muggle - borns shouldn't marry, while Hermione's friends might be sympathetic towards her and critical of Draco.
Some in the wizarding community might be secretly glad. Those who still hold onto pure - blood ideals may think that Draco is better off without a Muggle - born wife like Hermione. They might see it as a restoration of sorts of the 'purity' of the Malfoy name. On the other hand, Hermione's friends and those who support Muggle - wizard relations would likely be sympathetic towards her. They would probably see Draco as the one at fault, believing that he couldn't fully accept Hermione for who she is.
However, there could also be those who are glad she's leaving. Some pure - blood supremacists might see her as a threat to their traditional views. They might think that with her gone, they can push their archaic ideas more freely in the wizarding world.
The wizarding world would be in chaos. Harry is seen as a hero and the 'Chosen One'. His death would leave a huge void. The Order of the Phoenix would be devastated and might seek revenge on Draco and those associated with him. Hogwarts would also be in turmoil, with students and teachers alike shocked and saddened. There would be a great deal of fear as well, as Voldemort's forces might see this as an opportunity to gain more power.
Hermione could become withdrawn. She might isolate herself from her friends for a while, spending her time in the library trying to make sense of it all. She might also feel a sense of betrayal, especially if they had some sort of understanding or relationship developing.
The wizarding world would be in shock. Harry is seen as a hero, and for him to kill Draco, even if Draco was from a 'less popular' side, would be a huge scandal. His friends like Hermione and Ron would be deeply conflicted. They would be torn between their loyalty to Harry and their disbelief at his actions.
One possibility could be through some sort of time - traveling or alternate universe scenario in the fanfiction. Maybe a spell gone wrong sent Hermione back in time and through a series of complex events, she ended up in a situation where she was related to Draco in that way. It's a very creative and out - of - the - box concept that fanfiction often explores.
Well, Draco could be very conflicted. On one hand, he has his own pride and his Slytherin upbringing which might tell him to stay away. But if he has developed deeper feelings for Hermione in the fanfic, he might put aside their past differences. He could start by using his family's resources to find a cure or at least better treatments for her cancer. He may also become more protective of her, keeping her away from those who might be unkind about her illness.
In the wizarding community, the reaction could be complex. The pure - blood families might be the most against it, seeing it as a stain on the so - called 'purity' of magic. Hogwarts students could also be split. Some of Hermione's friends might support her, while others might be confused or even turn their backs on her. The teachers, too, would have different opinions. Dumbledore, perhaps, would be more understanding, while some of the stricter teachers might oppose it.
The wizarding community would likely be in shock. Hermione is known for her association with Harry and Ron, and for her fight against the dark side. Marrying Rowle, who might be associated with dark magic, would make many question her motives. Some might think she's gone to the dark side herself, while others might suspect there's more to the story than meets the eye.
She might be initially shocked. After all, Draco is usually seen as this tough Slytherin. But then she could feel sympathy. For instance, she might offer him a handkerchief without saying much at first.