A really interesting plot twist could be that female Naruto is actually from an alternate dimension where she and Kakashi are already married. In this new world, things are different, and she has to figure out how to make their relationship work in this dimension too. Plus, there could be a character who is jealous of their union and tries to break them apart by spreading false rumors about Kakashi's past, which female Naruto has to deal with.
One possible plot twist could be that their relationship is initially opposed by the village elders. They might see it as unconventional or worry about how it could affect Naruto's role as a potential Hokage. Another twist could be that an old enemy resurfaces and targets Kakashi to get to Naruto, seeing their marriage as a weakness to exploit.
One possible plot twist could be that Hanare is actually a spy from an enemy village but has truly fallen in love with Kakashi. She has to choose between her loyalty to her village and her love for him. Another could be that just before the wedding, Kakashi discovers a long - lost family secret that makes him question whether he should get married. For example, he might find out that his family has some sort of curse that could affect Hanare.
One possible plot twist could be that Anko is initially hesitant about the marriage due to her past traumas. Maybe she has some secrets she's afraid to share with Kakashi. For example, her past association with Orochimaru might make her doubt her own worthiness in a relationship. Another plot twist could be external threats to their marriage. The shinobi world is full of danger, and perhaps an enemy targets Anko to get to Kakashi, or vice versa. This could put a strain on their relationship as they try to protect each other while also dealing with the normal stresses of a new marriage.
One possible plot twist could be that they face opposition from their respective clans who still hold grudges from the past. The Uchiha clan might not accept Naruto easily due to his connection to the Nine - Tails. Another twist could be that Sasuke discovers a new power within herself during their marriage that has unforeseen consequences for the village. Maybe it attracts enemies who want to steal that power.
A third plot twist could be the appearance of an old enemy from either of their worlds. For instance, if one of Naruto's old foes teams up with an enemy from Esdeath's world. They would then have to put aside their differences and work together to defeat the common enemy, which could either strengthen or strain their marriage.
One possible plot twist could be that Naruto has to face a powerful enemy right before the wedding. This enemy might be someone from his past who wants to disrupt his happiness. Another could be that Hana discovers a long - lost relative who has some secrets about her family that could change their relationship. Or perhaps there's a mix - up with the wedding arrangements, like the wrong venue being booked, which leads to a series of comical and heartwarming events as they try to fix it.
A plot twist could be that Ayame is actually part of a prophecy related to Naruto. For example, their marriage is foretold to bring either great prosperity or great disaster to the Hidden Leaf Village. This makes their relationship more than just a love story and puts a lot of pressure on them, as they have to figure out how to fulfill the prophecy in a positive way.
One possible plot twist could be that their marriage causes a rift in the ninja world. Some might oppose it due to Itachi's past actions. Another could be that they discover a new power that comes with their union, which is crucial in saving the world from a new threat. And perhaps they have to deal with family issues, like Naruto trying to make Itachi feel welcome in Konoha despite his past.
One possible plot twist could be that right before the wedding, Naruto has to go on a dangerous mission. This could put their relationship to the test as Sakura has to deal with the fear of losing him. She might even consider calling off the wedding. Another plot twist could be that an old enemy resurfaces and tries to use Sakura as a leverage against Naruto, forcing him to make a difficult choice between his love and the safety of the village.
One possible plot twist could be that Naruto discovers a long - lost family secret that has an impact on his marriage to Kurenai. Maybe it's a prophecy that his family was supposed to stay away from certain clans, and Kurenai's clan is one of them. This would create a lot of internal conflict for Naruto as he loves Kurenai but also feels a sense of duty to his family's legacy.