The following are some examples of the female lead dying in the ending of the anime: 1. Mitsukasa Ackerman in " The Attacking Giant ": In the ending, Mitsukasa and Allen used the giant-like ability to become the giant, Reiner Braus. They fought until the end but were eventually swallowed by the giant and died. "Your Name." In the ending, Su Zi chose to commit suicide because she missed him. She didn't meet the male lead or go to a new place with others. 3. The female protagonist of The Stone of Destiny, Grella Shapek: In the ending, due to the time distortion caused by the experiment, Grella and her assistant Barney eventually walked into different futures, and Grella finally chose to leave this world. 4. Kimki Ken in " Tokyo Ghoul ": In the ending, Kimki Ken became a " ghoul " due to being infected by the ghoul virus and eventually sacrificed himself to protect other humans. It should be noted that although the ending of these female protagonists was somewhat tragic, it did not necessarily mean that their storyline in the anime was bad or not worthy of sympathy.