There aren't many significant differences. The anime mostly sticks to the manga's plot and characters.
Overall, the anime of No Game No Life is quite similar to the manga. Some minor details might be tweaked for better animation presentation, but the core elements remain the same. For example, the character designs and key events are largely intact.
The No Game No Life anime is a relatively faithful adaptation of the manga. It maintains the main storylines and character developments. However, there could be some slight changes in the pacing or emphasis on certain scenes to fit the animation format and viewer engagement.
The best chapter pointer here is Chapter 288, "The Old Master Already Knows". It opens with Jiang Li and Zhao Lang were lifted onto stretchers and taken to Central... and closes on Fortunately, the doctor had also said that all Jiang Li suffered from was....
If you want the clearest chapter reference, go to Chapter 247. Early on, Facts have proved that arch-enemies often understand each other the best.; later, the chapter leans on It was barely dawn, and Jiang Yan had already had a meltdown..
If you want the clearest chapter reference, go to Chapter 220. Early on, I know everyone has many questions, and I'm here to answer them one by...; later, the chapter leans on Actually, from the very beginning of the seed selection phase, we designed....
A practical answer is Chapter 230, because it turns the idea into a concrete scene. The chapter opens with Shang Shaojing's expression wasn't looking too good either., adds pressure through Is this how you treat my daughter?!, and ends on If he knew that your stepmother was secretly prompting you.
Look to Chapter 268 for the clearest answer. It begins with To ensure the company's successful listing, Shen Lan even went so far as..., keeps building through Everyone thought she was doomed to lose, but she managed to turn the..., and lands on Jiang Li has nothing to do with Director Sun!".
A practical answer is Chapter 242, because it turns the idea into a concrete scene. The chapter opens with Just when Jiang Yan called to heaven and earth in vain, he looked up and..., adds pressure through Young Master Jiang, it sounds like someone is at the door, aren't you..., and ends on Just.
Chapter 235 is the strongest chapter-level answer because it starts from Chasing Wind Youth was clearly becoming anxious, and as a result, his... and follows through on Indeed, he had endured many accidents while traveling around these past....
The best chapter pointer here is Chapter 227, "There's Something Wrong with This Stepmother". It opens with Your Four Pillars of Destiny is very strong, with wealth, authority, and... and closes on Your three palaces are prosperous, and correspondingly, your marriage....
A practical answer is Chapter 228, because it turns the idea into a concrete scene. The chapter opens with Huo Ziyang had not stepped out of the house for a whole week., adds pressure through She would never allow such scum in her family!, and ends on Why did you hit Ziyang?" Huo Xuan, one hand.
If you want the clearest chapter reference, go to Chapter 239. Early on, I can't believe it, I thought the live broadcast was over, but here's a...; later, the chapter leans on Now, they have to vote for who transformed the most successfully..