In this kind of fanfiction, Goku might lose his family. For example, his friends and loved ones could be killed by a powerful new enemy. This would leave him in a state of deep despair and loneliness, and he would have to find a way to carry on without them.
Perhaps Goku loses his powers completely. He could be hit by a strange new technique that strips him of his Saiyan abilities. Without his powers, he'd have to rely on his wits and the skills he learned before becoming a super - powerful fighter. He might start training all over again from scratch, facing many difficulties along the way.
One possibility is that Goku loses his reputation. Maybe he is framed for a crime he didn't commit. This would turn his friends against him, and he would have to prove his innocence while also dealing with the loss of trust from those he cares about. It would be a huge challenge for him as he's always been seen as a hero in the Dragon Ball Z universe.
Chapter 520, "Was Zheng Xun Replaced?!", is the clearest early answer because it turns Zheng Xun's situation into a concrete plot event. Early on, What did it mean that Jin Siyue had already given him all the shares?!.
Chapter 544, "I Shouldn't Have Stopped You from Pursuing Shang Shaojing Back Then", is the clearest early answer because it turns Bai Lu's situation into a concrete plot event.
Chapter 469, "He Must Not Tolerate This Calamity", is the clearest early answer because it turns Children Palace's situation into a concrete plot event. The chapter turns that into something concrete by moving from There was no other choice, so Jiang Li and the others hastily turned...
Chapter 499, "Jiang, the Malicious Merchant is Online Again", is the clearest early answer because it turns Jiang Yan's situation into a concrete plot event.
Chapter 752, "The Sudden and Unforeseen Reversal", is the clearest early answer because it turns Shu Yan's situation into a concrete plot event. The chapter gives readers a real answer by opening on By what right do you arrest my son?!" Upon hearing the commotion, Mrs.
Chapter 493, "Affinity Only 50 Now?!", is the clearest early answer because it turns Zheng Xun's situation into a concrete plot event. Early on, You!" Shang Shaojing was so annoyed he gritted his teeth, "Jiang Yan,....
Chapter 532, "Little Lolita Beats Up Jungle Python?!", is the clearest early answer because it turns Zhou Xu's situation into a concrete plot event. The chapter turns that into something concrete by moving from Outside the cave, the four people grasped their weapons tightly and...
Chapter 791, "There's Actually a Suona?!", is the clearest early answer because it turns Jiang Shixu's situation into a concrete plot event. It opens with The lights in the audience suddenly went out, and immediately, the...
Chapter 460, "Saving People", is the clearest early answer because it turns Yu Li's situation into a concrete plot event. It opens with [HAHAHAHAHAHAHA, Jiang Yan is impersonating me.] [At this moment, I... and closes on Dare to attack me in hiding?!.
Chapter 829, "How can you not even keep an eye on one person?!", is the clearest early answer because it turns Ji Yanbai's situation into a concrete plot event.