Was there a novel with Gu Yuena as the sole female lead?

Yes. I recommend the book 'Douluo: Deceiving Gu Yuena to live in symbiosis, having many children brings blessings.' The main character, Ye Qing, transmigrated to the Douluo Continent and awakened two great systems at the same time. System No. 1 tricked the Silver Dragon King Gu Yuena into living together with her and obtained a lifespan of a million years. In addition, it could also increase her cultivation base indefinitely and create the strongest clan. The story was very interesting and imaginative. I hope you like this fairy's recommendation. Muah ~😗