The large amount of mana changing flow around the world caused many mages to be broken from meditation. This wasn't the only thing though. Plenty of those with a greater sensitivity for mana in general sensed it all too clearly.
While this was nothing dangerous, it did cause the rune carvers worries. This was because the elemental rune formations were affected for a slight time. Proving that all the safeguards to protect their rune formations had been incredibly valuable. But the older rune formations were damaged causing many different reactions.
The break down fo the peddler runes forced Genesis and other kingdoms to begin their action plans for just this situation.
Within the Genesis building, it had been theorized that the changes in mana across the world might have various effects. Besides the chances that monsters, plants, and people would change, there was the fact that existing aspects of their kingdoms would be affected.