Poison

"He's the reason Hera Cruel died."

Being a princess of the most notorious couple that was matched made in hell made her life far more dangerous even as a child. Although growing up, she was able to grow numb and deal with it, it was not enough. People died just tasting her food, and she lost countless men so she could live. Therefore, when Hera managed to build her power and influence as the respectable and fearsome don of the Cruel crime family, she thought of building tolerance towards drugs and poison. 

Everyone was against the idea. That was akin to suicide. Who in their sound mind would do that? She had men — capable men who were willing to die for her. This idea was dangerous, but despite everyone's disapproval, Hera called the shots.

Thus, she pushed through the plan.