Definitely. Spiderman is the original and broader comic franchise, but The Amazing Spider-Man has distinct plotlines and maybe a different focus or style. They have some common elements but also significant differences.
Spiderman's sexuality in the comics is a complex matter. While there have been instances that could be interpreted as bisexuality, it's not a straightforward or widely established aspect of the character.
I'm pretty sure there isn't a Michelle in the Spiderman comics. The comic characters are pretty well-defined, and Michelle isn't one of them. But you never know, there could be a new character introduced in future issues.
Spiderman is not gay in the comics. The character's romantic relationships have mainly been with female characters, which is consistent throughout the majority of the comic series.