Most of the time, Borderlands comics are canon. They provide additional background and depth to the Borderlands universe. However, there might be some cases where specific elements could be subject to interpretation or change depending on future developments in the franchise.
The story length in Borderlands 2 can vary depending on your playstyle and how much you explore. Generally, it can take around 20-30 hours to complete the main storyline.
The story of Borderlands 3 usually lasts for approximately 35 to 45 hours. This includes the main quests and some side activities. However, if you're a completionist and want to do everything, it could take even longer.