Tanjiro's strength in the manga is significant. He acquires new powers and techniques, and overcomes numerous powerful foes with determination and strategy.
The Hashiras would likely show concern. Some, like Shinobu, would immediately start looking into possible medical solutions. Giyuu might be more reserved in his worry but would still keep a close eye on Tanjiro. The other demon slayers would also be affected. They look up to Tanjiro, so his sickness would lower the morale of the group. They would try to support each other while waiting for Tanjiro to recover.
It's hard to give an exact number. Different story arcs and battles led to the deaths of multiple hashira. Some died heroically, while others met their fate in unexpected ways. The count changes as the manga progresses.
Tanjiro might use his sense of smell to detect hidden threats. Since his sense of smell is super - enhanced, he could sniff out any demons or traps in the way of saving Rengoku. For example, if there are demons disguised as allies, Tanjiro would be able to tell by their scent.
Well, Tanjiro's fate in the manga is tied to his determination to save others and the ultimate confrontation with powerful foes. His death comes as a poignant end to his heroic journey.
Tanjiro is believed to be 18 by the manga's end. This age is a result of the events and time that has passed since the beginning of the story, showing his maturation and development.