In 'deku meets future deku fanfiction', perhaps the future Deku warns the present one about upcoming threats. He could tell him about villains he'll face in the future and how to defeat them. This would give the present Deku an edge in his battles and also in his growth as a hero.
In such fanfiction, Sakura might be depicted as more alluring and perhaps more bold in her interactions with Madara. Madara could be shown as having a certain charm that draws Sakura to him.
One possible plot could be that Villain Deku is on a mission to undermine the hero society and crosses paths with Hero Deku. They engage in a fierce battle where Villain Deku taunts Hero Deku about his ideals. In the end, Hero Deku manages to get through to a small part of Villain Deku's conscience, leaving him with some doubts about his villainous path.
Another plot might involve the older Deku being from an alternate timeline. He shows the younger Deku different ways he could have developed his skills and relationships, which makes the younger Deku reevaluate his own path as a hero.
In the manga, Deku experiences various ups and downs. He not only becomes stronger physically but also matures emotionally as he takes on greater responsibilities. There are also many unexpected plot twists that shape his journey.
It could lead to a completely different character dynamic and story arc. Maybe she'd face different challenges and have a unique perspective on being a hero.
Perhaps he sees her as a threat. Sakura is a skilled kunoichi, and Madara may want to prevent her from interfering in his plans. So he restrains her to keep her out of the way.
The main differences are in their expressions and some minor details of personality. In the manga, Deku might seem a bit more intense, while in the anime, he's sometimes presented a bit softer.
One possible motive could be a long - held grudge that has festered over time. Maybe Bakugou's constant bullying in their past finally pushed Deku over the edge. Another could be some sort of mind - control or dark influence that made Deku act out of character.